Quinolizine derivatives

Claim 1

A PROCESS WHICH COMPRISES MIXING HOMOPIPERONYLAMINE WITH LOWER ALKOXYMALONYL HALIDE, THEREBY PRODUCING LOWER ALKOXYMALONYL-HOMOPIPERONYLAMIDE, CYCLIZING THE LATTER BY HEATING WITH PHOSPHORUS OXYCHLORIDE, THEREBY PRODUCING 1-LOWER CARBALKOXYMETHYL-6,7-METHYLENEDIOXY-3,4-DIHYDROISOQUINOLINE, PARTIALLY HYDROGENATING THE LATTER BY CATALYTIC HYDROGENATION IN THE PRESENCE OF A PLATINUM HYDROGENATION CATALYST, THEREBY PRODUCING 1-LOWER CARBALKOXMETHYL- AND WITH A-LOWER ALKYL-MALONIC ACID HYDROISOQUINOLINE, CONDENSING THE LATTER BY HEATING WITH A MEMBER OF THE GROUP CONSISTING OF FORMALDEHYDE AND PARAFORMALDEHYDE AND WITH A-LOWER ALKYL-MALONIC ACID DIMETHYL ESTER, THEREBY PRODUCING 1-LOWER CARBALKOXYMETHYL - 2 - (2,2 - DICARBOMETHOXY-2-LOWER ALKYL - ETHYL)6,7 - METHYLENEDIOXY - 1,2,3,4 - TETRAHYDROISOQUINOLINE, CYCLIZING THE LATTER BY HEATING WITH AN ALKALI METAL ALKOXIDE, THEREBY PRODUCING 1-LOWER CARBALKOXY-2-OXO-3-CARBOMETHOXY - 3 - LOWER ALKYL-9,10-METHYLENEDIOXY-1,2,3,4,6,7HEXAHYDRO-11B-BENZO(A) QUINOLIZINE, AND HYDROLYZING AND DECARBOXYLATING THE LATTER BY HEATING WITH AN AQUEOUS SOLUTION OF A MINERAL ACID, THEREBY PRODUCING 2-OXO-3-LOWER ALKYL-9,10-METHYLENEDIOXY - 1,2,3,4,6,7 - HEXAHYDRO - 11BBENZOL(A) QUINOLIZINE.