Patent US2765302A successfully refreshed from Google Patents.
US2765302A
Expired / Lapsed
US
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Process for the purification of streptomycin
Assignee: Olin Corp
•
Filing: 1953-03-16
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Granted: 1956-10-02
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Expires: 1973-03-16
Abstract
No abstract record available.
Inventors
- 👤 Charles R Bartels
- 👤 Berk Bernard
- 👤 Wilbur L Bryan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 22:29
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/238; Y; Y10; Y10S; Y10S424/00; Y10S424/06
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
98 words
PROCESS FOR PURIFYING STREPTOMYCINS WHICH COMPRISES ADSORBING A STREPTOMYCIN-CONTAINING BROTH FILTRATE, AT A PH ABOVE ABOUT 5, ON A FIRST COLUMN CONTAINING A CATION EXCHANGE RESIN, ELUTING THE ADSORBED STREPTOMYCIN FROM THE COLUMN WITH A MINERAL ACID AT A PH ABOUT 1 TO 3, ADJUSTING THE ELUATE TO A PH AT LEAST ABOUT 8, ADDING TO THE ELUATE AN ALKALINE-EARTH-METAL SEQUESTERING AGENT IN QUANTITY AT LEAST SUFFICIENT TO SEQUESTER THE ALKALINEEARTH-METAL IONS, ADSORBING THE STREPTOMYCIN FROM THE RESULTING SOLUTION ON A SECOND COLUMN CONTAINING A CATION EXCHANGE RESIN, THEN PREFERENTIALLY ELUTING A PURIFIED STREPTOMYCIN FROM SAID SECOND COLUMN.
Claim 2
Dependent Claim
98 words
PROCESS FOR PURIFYING STREPTOMYCINS WHICH COMPRISES ADSORBING A STREPTOMYCIN-CONTAINING BROTH FILTRATE, AT A PH ABOVE ABOUT 5, ON A FIRST COLUMN CONTAINING A CATION EXCHANGE RESIN, ELUTING THE ADSORBED STREPTOMYCIN FROM THE COLUMN WITH A MINERAL ACID AT A PH ABOUT 1 TO 3, ADJUSTING THE ELUATE TO A PH AT LEAST ABOUT 8, ADDING TO THE ELUATE AN ALKALINE-EARTH-METAL SEQUESTERING AGENT IN QUANTITY AT LEAST SUFFICIENT TO SEQUESTER THE ALKALINEEARTH-METAL IONS, ADSORBING THE STREPTOMYCIN FROM THE RESULTING SOLUTION ON A SECOND COLUMN CONTAINING A CATION EXCHANGE RESIN, THEN PREFERENTIALLY ELUTING A PURIFIED STREPTOMYCIN FROM SAID SECOND COLUMN.
References Cited (Backward Citations)
US2528022A
Cited
US2550939A
Cited
US2521770A
Cited
US2655497A
Cited
US2541420A
Cited
US2656300A
Cited
US2528188A
Cited
US2656347A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1959-10-02 | 1960-04-02 | 1960-10-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1963-10-02 | 1964-04-02 | 1964-10-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1967-10-02 | 1968-04-02 | 1968-10-02 | $7700.00 | Window Closed / Lapsed |