Process for the manufacture of 8-hydroxy quinoline

Claim 1

THE PROCESS FOR THE PREPARATION OF 8-HYDROXY QUINOLINE BY THE REACTION OF GLYCEROL, ORTHOAMINOPHENOL, CONCENTRATED SULFURIC ACID AND ORTHO-NITROPHENOL IN THE PRESENCE OF AN INORGANIC OXYGEN CARRIER SELECTED FROM THE GROUP CONSISTING OF COMPOUNDS OF IRON, COBALT AND NICKEL WHICH ARE SOLUBLE IN THE REACTION MIXTURE WHICH COMPRISES EFFECTING PRELIMINARY INTERMIXTURE OF THE GLYCOL, CONCENTRATED SULFURIC ACID CONTAINING NOT MORE THAN 5 PER CENT BY WEIGHT OF WATER AND ORTHO-AMINOPHENOL BY ADDING THE ORTHO-AMINOPHENOL GRADUALLY TO THE CONCENTRATED SULFURIC ACID WHILE MAINTAINING THE TEMPERATURE AT FROM 70* TO 80* C., AND THEN ADDING THE GLYCEROL GRADFUALLY TO THE RESULTING MIXTURE WHILE MAINTAINING THE TEMPERATURE AT FROM 70* TO 80* C., GRADUALLY ADDING THE RESULTING MIXTURE WHILE AT A TEMPERATURE OF NOT OVER 120* C. TO A MIXTURE OF THE ORTHO-NITROPHENOL AND THE INORGANIC OXYGEN CARRIER IN A REACTION ZONE AT SUCH A RATE THAT THE TEMPERATURE IN THE REACTION ZONE DOES NOT EXCEED 140* C., AND THEREAFTER REFLUXING THE REACTION MIXTURE AT A TEMPERATURE OF NOT OVER 140* C. UNTIL REACTION IS SUBSTANTIALLY COMPLETE.