Patent US2543215A successfully refreshed from Google Patents.
US2543215A
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Process of preparing antibody-rich globulin fractions
Assignee: Wisconsin Alumni Research Foundation
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Filing: 1947-06-03
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Granted: 1951-02-27
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Expires: 1967-06-03
Abstract
No abstract record available.
Inventors
- 👤 John W Williams
- 👤 Harold F Deutsch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:05
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/06; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/83; Y10S530/831
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
120 words
THE PROCESS OF PREPARING ANTIBODY-ACTIVE GAMMA GLOBULIN PREPARATIONS FROM ANILAL BLOODD SERUM CONTAINING ANTIBODIES WHICH COMPRISES DILUTING THE SERUM WITH WATER, ADJUSTING THE DILUTED SERUM SYSTEM TO A PH OF ABOUT 7.4-8.2, COOLING THE ALKALINE SERUM SYSTEM TO NEAR ITS FREEZING POINT, ADDING COLD AQUEOUS ETHANOL TO THE COOLED SERUM SYSTEM UNTIL TH FINAL CONCENTRATION OF THE ETHANOL IS ABOUT 15-30 PER CENT BY VOLUME AND THE IONIC STRENGTH OF THE SYSTEM IS ABOUT 0.01 TO 0.04, MAINTAINING THE TEMPERATURE OF THE SYSTEM DURING THE ADDITION OF THE ETHANOL CLOSE TO ITS FREEZING POINT BY REDUCING THE TEMPERATURE OF THE SYSTEM UNTIL THE TEMPERATURE IS ABOUT -6* C., AND RECOVERING THE RESULTING ANTIBODY-RICH PRECIPITATE FROM THE COLD AQUEOUS ETHANOL SOLUTION.
Claim 2
Dependent Claim
120 words
THE PROCESS OF PREPARING ANTIBODY-ACTIVE GAMMA GLOBULIN PREPARATIONS FROM ANILAL BLOODD SERUM CONTAINING ANTIBODIES WHICH COMPRISES DILUTING THE SERUM WITH WATER, ADJUSTING THE DILUTED SERUM SYSTEM TO A PH OF ABOUT 7.4-8.2, COOLING THE ALKALINE SERUM SYSTEM TO NEAR ITS FREEZING POINT, ADDING COLD AQUEOUS ETHANOL TO THE COOLED SERUM SYSTEM UNTIL TH FINAL CONCENTRATION OF THE ETHANOL IS ABOUT 15-30 PER CENT BY VOLUME AND THE IONIC STRENGTH OF THE SYSTEM IS ABOUT 0.01 TO 0.04, MAINTAINING THE TEMPERATURE OF THE SYSTEM DURING THE ADDITION OF THE ETHANOL CLOSE TO ITS FREEZING POINT BY REDUCING THE TEMPERATURE OF THE SYSTEM UNTIL THE TEMPERATURE IS ABOUT -6* C., AND RECOVERING THE RESULTING ANTIBODY-RICH PRECIPITATE FROM THE COLD AQUEOUS ETHANOL SOLUTION.
References Cited (Backward Citations)
US2390074A
Cited
US2437060A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1954-02-26 | 1954-08-28 | 1955-02-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1958-02-26 | 1958-08-28 | 1959-02-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1962-02-26 | 1962-08-28 | 1963-02-27 | $7700.00 | Window Closed / Lapsed |