Patent US4086005A successfully refreshed from Google Patents.
Patent US2501014A successfully refreshed from Google Patents.
US2501014A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of obtaining highly-purified streptomycin acid-addition salts
Assignee: ER Squibb and Sons LLC
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Filing: 1946-05-01
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Granted: 1950-03-21
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Expires: 1966-05-01
Abstract
No abstract record available.
Inventors
- 👤 Wintersteiner Oskar
- 👤 Fried Josef
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 16:34
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/238
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
72 words
THE METHOD WHICH COMPRISES REACTING A PARTIALLY-PURIFIED, WATER-SOLUBLE STREPTOMYCIN ACID-ADDITION SALT WITH PICRIC ACID IN AQUEOUS SOLUTION, DISSOLVING THE RESULTING PICRATE IN ON ORGANIC SOLVENT THEREFOR, PASSING THE SOLUTION THROUGH A CHROMATOGRAPHIC ADSORPTION COLUMN, ELUTING THE STREPTOMYCIN-RICH SECTIONS OF THE CHROMATOGRAM WITH AN AQUEOUS, WATER-MISCIBLE ORGANIC SOLVENT FOR STREPTOMYCIN PICRATE, DECOMPOSING THE ELUTED PICRATE WITH A STRONG MINERAL ACID, AND SEPARATING THE ORGANIC SOLVENT AND PICRIC ACID FROM THE STREPTOMYCIN SALT FORMED.
Claim 2
Independent Claim
72 words
THE METHOD WHICH COMPRISES REACTING A PARTIALLY-PURIFIED, WATER-SOLUBLE STREPTOMYCIN ACID-ADDITION SALT WITH PICRIC ACID IN AQUEOUS SOLUTION, DISSOLVING THE RESULTING PICRATE IN ON ORGANIC SOLVENT THEREFOR, PASSING THE SOLUTION THROUGH A CHROMATOGRAPHIC ADSORPTION COLUMN, ELUTING THE STREPTOMYCIN-RICH SECTIONS OF THE CHROMATOGRAM WITH AN AQUEOUS, WATER-MISCIBLE ORGANIC SOLVENT FOR STREPTOMYCIN PICRATE, DECOMPOSING THE ELUTED PICRATE WITH A STRONG MINERAL ACID, AND SEPARATING THE ORGANIC SOLVENT AND PICRIC ACID FROM THE STREPTOMYCIN SALT FORMED.
Claim 3
Independent Claim
37 words
THE METHOD OF OBTAINING A SUBSTANTIALLYPURE STREPTOMYCIN ACID-ADDITION SALT WHICH COMPRISES DECOMPOSING A CRYSTALLINE STREPTOMYCIN REINEKATE WITH A WATER-SOLUBLE SALT OF A METAL FORMING AN INSOLUBLE REINEKATE, REMOVING THE PRECIPITATE, AND RECOVERING THE RESULTING SUBSTANTIALLY-PUR STREPTOMYCIN SALT.
Claim 4
Independent Claim
37 words
THE METHOD OF OBTAINING A SUBSTANTIALLYPURE STREPTOMYCIN ACID-ADDITION SALT WHICH COMPRISES DECOMPOSING A CRYSTALLINE STREPTOMYCIN REINEKATE WITH A WATER-SOLUBLE SALT OF A METAL FORMING AN INSOLUBLE REINEKATE, REMOVING THE PRECIPITATE, AND RECOVERING THE RESULTING SUBSTANTIALLY-PUR STREPTOMYCIN SALT.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1953-03-20 | 1953-09-19 | 1954-03-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1957-03-20 | 1957-09-19 | 1958-03-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1961-03-20 | 1961-09-19 | 1962-03-21 | $7700.00 | Window Closed / Lapsed |