US20050149022A1 — Curable media for implantable medical device

Claim 1

Independent Claim 79 words

1 . A formed in place orthopedic device, comprising: an outer wall, defining a cavity therein; and a hardenable media within the cavity to form the orthopedic device, said hardenable media comprising a resin and hardener mixture that is substantially cured at a temperature below about 45° C. in about 90 minutes or less; wherein the hardenable media is hardened while the device is positioned within the body of a patient to create the formed in place orthopedic device.

Claim 2

Dependent Claim 79 words

1 . A formed in place orthopedic device, comprising: an outer wall, defining a cavity therein; and a hardenable media within the cavity to form the orthopedic device, said hardenable media comprising a resin and hardener mixture that is substantially cured at a temperature below about 45° C. in about 90 minutes or less; wherein the hardenable media is hardened while the device is positioned within the body of a patient to create the formed in place orthopedic device.

Claim 3

Dependent Claim 20 words

2 . The formed in place orthopedic device of claim 1 , wherein said hardenable media comprises an epoxy resin.

Claim 4

Dependent Claim 45 words

3 . The formed in place orthopedic device of claim 2 , wherein said epoxy resin comprises a total of about 65-75% by weight of one or more diepoxide resins and a total of about 25-35% by weight of one or more amine curing agents.

Claim 5

Dependent Claim 40 words

4 . The formed in place orthopedic device of claim 2 , wherein said epoxy resin comprises about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines.

Claim 6

Dependent Claim 29 words

5 . The formed in place orthopedic device of claim 4 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A or diglycidyl ether of Bisphenol F.

Claim 7

Dependent Claim 26 words

6 . The formed in place orthopedic device of claim 4 , wherein the aliphatic diepoxide resin comprises one or more alkane diols of glycidyl ether.

Claim 8

Dependent Claim 31 words

7 . The formed in place orthopedic device of claim 4 , wherein the dialkylamines are according to the formula H2N—R—NH2, wherein R is a branched or unbranched C2-C10 alkyl group.

Claim 9

Dependent Claim 17 words

8 . The formed in place orthopedic device of claim 4 , wherein the cycloalkylamines are N-aminoalkylpiperazines.

Claim 10

Dependent Claim 42 words

9 . The formed in place orthopedic device of claim 4 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A, the aliphatic diepoxide resin comprises butane diol of glycidyl ether, the dialkylamine comprises 1,3-diaminopropane, and the cycloalkylamine comprises N-aminoethylpiperazine.

Claim 11

Dependent Claim 34 words

10 . The formed in place orthopedic device of claim 1 , wherein said hardenable media cures to a hardened form having a static compression bending value (ASTM F1717) of at least 100 lbs.

Claim 12

Dependent Claim 5 words

11 .- 19 . (canceled)

Claim 13

Dependent Claim 5 words

11 .- 19 . (canceled)

Claim 14

Dependent Claim 111 words

20 . An orthopedic fixation device, comprising: an elongate, flexible tubular body having a distal end and a proximal end, said body forming a central lumen; a manifold at the proximal end of the tubular body comprising at least one port; an inflatable member having a proximal end, a distal end, and an interior, removably attached to the distal end of the tubular body; a hardenable media for inflating said inflatable member, said hardenable media comprising about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines; and a valve, provided at the proximal end of the inflatable member.

Claim 15

Dependent Claim 111 words

20 . An orthopedic fixation device, comprising: an elongate, flexible tubular body having a distal end and a proximal end, said body forming a central lumen; a manifold at the proximal end of the tubular body comprising at least one port; an inflatable member having a proximal end, a distal end, and an interior, removably attached to the distal end of the tubular body; a hardenable media for inflating said inflatable member, said hardenable media comprising about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines; and a valve, provided at the proximal end of the inflatable member.

Claim 16

Dependent Claim 63 words

21 . The orthopedic fixation device of claim 20 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A or diglycidyl ether of Bisphenol F; the aliphatic diepoxide resin comprises one or more alkane diols of glycidyl ether; the cycloalkylamines are N-aminoalkylpiperazines; and the dialkylamines are according to the formula H2N—R—NH2, wherein R is a branched or unbranched C2-C10 alkyl group.

Claim 17

Dependent Claim 40 words

22 . The orthopedic fixation device of claim 21 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A, the aliphatic diepoxide resin comprises butane diol of glycidyl ether, the dialkylamine comprises 1,3-diaminopropane, and the cycloalkylamine comprises N-aminoethylpiperazine.

Claim 18

Dependent Claim 29 words

23 . The orthopedic fixation device of claim 20 , wherein said hardenable media, when cured, has a static compression bending value of at least 100 lbs (ASTM F1717).

Claim 19

Dependent Claim 22 words

24 . The orthopedic fixation device of claim 20 , wherein the media is substantially cured in about 90 minutes or less.

Claim 20

Dependent Claim 23 words

25 . The orthopedic fixation device of claim 20 , wherein the media cures at a temperature of about 45° C. or less.

Claim 21

Dependent Claim 81 words

26 . A method of forming an orthopedic device at a treatment site within the body of a patient, comprising the steps of: positioning an outer wall at the treatment site within the patient, the outer wall defining a chamber therein; and introducing a hardenable media into the chamber, wherein the hardenable media cures from a liquid form to a hardened form having a static compression bending value of at least 90 lbs (ASTM F1717) in about 90 minutes or less.

Claim 22

Dependent Claim 81 words

26 . A method of forming an orthopedic device at a treatment site within the body of a patient, comprising the steps of: positioning an outer wall at the treatment site within the patient, the outer wall defining a chamber therein; and introducing a hardenable media into the chamber, wherein the hardenable media cures from a liquid form to a hardened form having a static compression bending value of at least 90 lbs (ASTM F1717) in about 90 minutes or less.

Claim 23

Dependent Claim 27 words

27 . A method of forming an orthopedic device as in claim 26 , wherein the positioning step comprises positioning the outer wall between two bone anchors.

Claim 24

Dependent Claim 36 words

28 . The method of claim 26 , wherein said hardenable media comprises about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines.

Claim 25

Dependent Claim 61 words

29 . The method of claim 28 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A or diglycidyl ether of Bisphenol F; the aliphatic diepoxide resin comprises one or more alkane diols of glycidyl ether; the cycloalkylamines are N-aminoalkylpiperazines; and the dialkylamines are according to the formula H2N—R—NH2, wherein R is a branched or unbranched C2-C10 alkyl group.

Claim 26

Dependent Claim 38 words

30 . The method of claim 28 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A, the aliphatic diepoxide resin comprises butane diol of glycidyl ether, the dialkylamine comprises 1,3-diaminopropane, and the cycloalkylamine comprises N-aminoethylpiperazine.

Claim 27

Dependent Claim 19 words

31 . The method of claim 26 , wherein the hardenable media cures at temperature below about 45° C.

Claim 28

Dependent Claim 28 words

32 . The method of claim 26 , wherein the hardenable media has a static compression bending value (ASTM F1717) of at least 150 lbs within 12 hours.

Claim 29

Dependent Claim 83 words

33 . A method of stabilizing an orthopedic fracture, comprising: inserting at least two anchors having portals into a bone; delivering an orthopedic device comprising an inflatable balloon to the bone; and inflating said balloon with a hardenable media comprising about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines; wherein said orthopedic device extends through said portals, such that said inflating fixes said anchors in relation to one another.

Claim 30

Dependent Claim 83 words

33 . A method of stabilizing an orthopedic fracture, comprising: inserting at least two anchors having portals into a bone; delivering an orthopedic device comprising an inflatable balloon to the bone; and inflating said balloon with a hardenable media comprising about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines; wherein said orthopedic device extends through said portals, such that said inflating fixes said anchors in relation to one another.

Claim 31

Dependent Claim 61 words

34 . The method of claim 33 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A or diglycidyl ether of Bisphenol F; the aliphatic diepoxide resin comprises one or more alkane diols of glycidyl ether; the cycloalkylamines are N-aminoalkylpiperazines; and the dialkylamines are according to the formula H2N—R—NH2, wherein R is a branched or unbranched C2-C10 alkyl group.

Claim 32

Dependent Claim 38 words

35 . The method of claim 33 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A, the aliphatic diepoxide resin comprises butane diol of glycidyl ether, the dialkylamine comprises 1,3-diaminopropane, and the cycloalkylamine comprises N-aminoethylpiperazine.

Claim 33

Dependent Claim 27 words

36 . The method of claim 33 , wherein said hardenable media, when cured, has a static compression bending value of at least 100 lbs. (ASTM F1717).

Claim 34

Dependent Claim 20 words

37 . The method of claim 33 , wherein the media is substantially cured in about 90 minutes or less.

Claim 35

Dependent Claim 21 words

38 . The method of claim 33 , wherein the media cures at a temperature of about 45° C. or less.

Claim 36

Dependent Claim 72 words

39 . A method of stabilizing an orthopedic fracture, comprising: inserting at least two anchors having portals into a bone; delivering an orthopedic device comprising an inflatable balloon through the portals; and inflating said balloon with a liquid curable material; wherein the inflating step fixes said anchors in relation to one another and the curable material is substantially cured at a temperature below about 45° C. in about 90 minutes or less.

Claim 37

Dependent Claim 72 words

39 . A method of stabilizing an orthopedic fracture, comprising: inserting at least two anchors having portals into a bone; delivering an orthopedic device comprising an inflatable balloon through the portals; and inflating said balloon with a liquid curable material; wherein the inflating step fixes said anchors in relation to one another and the curable material is substantially cured at a temperature below about 45° C. in about 90 minutes or less.

Claim 38

Dependent Claim 36 words

40 . The method of claim 39 , wherein said curable material comprises about 45-52% by weight aromatic diepoxide resin, about 19-23% by weight aliphatic diepoxide resin, about 20-29% by weight dialkylamines and about 4-9% cycloalkylamines.

Claim 39

Dependent Claim 61 words

41 . The method of claim 40 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A or diglycidyl ether of Bisphenol F; the aliphatic diepoxide resin comprises one or more alkane diols of glycidyl ether; the cycloalkylamines are N-aminoalkylpiperazines; and the dialkylamines are according to the formula H2N—R—NH2, wherein R is a branched or unbranched C2-C10 alkyl group.

Claim 40

Dependent Claim 38 words

42 . The method of claim 40 , wherein the aromatic diepoxide resin comprises diglycidyl ether of Bisphenol A, the aliphatic diepoxide resin comprises butane diol of glycidyl ether, the dialkylamine comprises 1,3-diaminopropane, and the cycloalkylamine comprises N-aminoethylpiperazine.

Claim 41

Dependent Claim 27 words

43 . The method of claim 39 , wherein said hardenable media, when cured, has a static compression bending value of at least 100 lbs. (ASTM F1717).

Claim 42

Dependent Claim 88 words

44 . A formed in place medical device, comprising: an outer wall, defining a cavity therein; and a hardenable media within the cavity to form the medical device, said hardenable media comprising a resin and hardener mixture that cures at a temperature below about 45° C. wherein said cured media has a static compression bending value (ASTM F1717) of at least 150 lbs; wherein the hardenable media is hardened while the device is positioned within the body of a patient to create the formed in place medical device.

Claim 43

Dependent Claim 88 words

44 . A formed in place medical device, comprising: an outer wall, defining a cavity therein; and a hardenable media within the cavity to form the medical device, said hardenable media comprising a resin and hardener mixture that cures at a temperature below about 45° C. wherein said cured media has a static compression bending value (ASTM F1717) of at least 150 lbs; wherein the hardenable media is hardened while the device is positioned within the body of a patient to create the formed in place medical device.

Curable media for implantable medical device

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