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Partial aortic occlusion devices and methods for cerebral perfusion augmentation

Assignee: Zoll Circulation Inc
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Filing: 2002-11-07
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Granted: —
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Expires: 2022-11-07
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Abstract

Abstract A method for increasing cerebral blood flow is described. A catheter is inserted into the descending aorta, the catheter having a proximal region, a distal region, and at least one expandable member mounted on the distal region. The expandable member is positioned downstream from the takeoff of the brachiocephalic artery. The expandable member is expanded to at least partially obstruct blood flow in the aorta. The expandable member is then cycled between greater and lesser obstruction of blood flow. In this manner, renal ischemia and lower limb ischemia is avoided.

Inventors

  • 👤 Jon St. Germain
  • 👤 Denise Barbut

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:43
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12027; A61B17/1204; A61B17/12045; A61B17/12036; A61B17/12099; A61B17/12109; A61B17/12131; A61B17/12136; A61B17/1214; A61B17/12145; A61B17/12181; A61B17/1219; A61B5/00; A61B5/02; A61B5/021; A61B5/0215; A61B5/40; A61B5/4076; A61B6/00; A61B6/48; A61B6/481; A61F; A61F7/00; A61F7/12; A61M; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M25/003; A61M25/0067; A61M25/0068; A61M25/008; A61M25/0082; A61M25/01; A61M25/0105; A61M25/0133; A61M25/0147; A61M25/10; A61M25/1011; A61B17/22; A61B2017/22051; A61B2017/22054; A61B90/00; A61B90/39; A61B2090/3966; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2002/068; A61F2007/126; A61M2025/0001; A61M2025/0002; A61M2025/0034; A61M2025/0073; A61M2025/0081; A61M2025/1043; A61M2025/1052; A61M2210/00; A61M2210/12; A61M2210/127; A61M2230/00; A61M2230/005; A61M2230/30; A61M25/0032; A61M25/0069; A61M25/0074; A61M25/06; A61M25/0662

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 88 words
1 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, and at least one expandable member mounted on the distal region; locating the at least one expandable member downstream from the takeoff of the brachiocephalic artery; expanding the at least one expandable member to at least partially obstruct blood flow in the aorta; and cycling the at least one expandable member between greater and lesser, obstruction of blood flow.
Claim 2
Dependent Claim 88 words
1 . A method for increasing cerebral blood flow, comprising the steps of: inserting a catheter into the descending aorta, the catheter having a proximal region, a distal region, and at least one expandable member mounted on the distal region; locating the at least one expandable member downstream from the takeoff of the brachiocephalic artery; expanding the at least one expandable member to at least partially obstruct blood flow in the aorta; and cycling the at least one expandable member between greater and lesser, obstruction of blood flow.
Claim 3
Dependent Claim 25 words
2 . The method of claim 1 , wherein the step of cycling the at least one expandable member is synchronized with the cardiac cycle.
Claim 4
Dependent Claim 25 words
3 . The method of claim 1 , wherein the step of cycling the at least one expandable member is independent of the cardiac cycle.
Claim 5
Dependent Claim 45 words
4 . The method of claim 1 , wherein the step of cycling the at least one expandable member produces a change in blood flow around the at least one expandable member to 80% of baseline during systole and to 20% of baseline during diastole.
Claim 6
Dependent Claim 45 words
5 . The method of claim 1 , wherein the step of cycling the at least one expandable member produces a change in blood flow around the at least one expandable member to 70% of baseline during systole and to 30% of baseline during diastole.
Claim 7
Dependent Claim 47 words
6 . The method of claim 1 , wherein the step of cycling the at least one expandable member produces a change in blood flow around the at least one expandable member to 80% of baseline for six cycles and to 20% of baseline for two cycles.
Claim 8
Dependent Claim 47 words
7 . The method of claim 1 , wherein the step of cycling the at least one expandable member produces a change in blood flow around the at least one expandable member to 70% of baseline for five cycles and to 10% of baseline for one cycle.
Claim 9
Dependent Claim 43 words
8 . The method of claim 1 , wherein the at least one expandable member is initially expanded to achieve 70% obstruction of blood flow in the aorta, and then is cycled between 60% and 80% obstruction of blood flow in the aorta.
Claim 10
Dependent Claim 34 words
9 . The method of claim 1 , further comprising the steps of measuring a physiologic parameter and adjusting the expansion of the at least one expandable member based on the measured physiologic parameter.
Claim 11
Dependent Claim 18 words
10 . The method of claim 1 , wherein the at least one expandable member comprises one balloon.
Claim 12
Dependent Claim 18 words
11 . The method of claim 1 , wherein the at least one expandable member comprises two balloons.

References Cited (Backward Citations)

US5486192A Cited

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