Plaster

Abstract

Abstract PURPOSE: To prepare a plaster free from sagging with age and giving cool and refreshing feeling to the skin, by coating a flexible substrate with a drug-containing layer obtained by adding a specific epoxy compound, etc. to a polyacrylic acid. CONSTITUTION: The objective plaster is prepared by coating a flexible substrate with a drug-containing hydrous gel layer composed mainly of a polyacrylic acid and/or its salt, water, a polyhydric alcohol, a compound having at least two epoxy groups (e.g. triglycidyl isocyanurate), an organic acid (e.g. citric acid) and an effective component (e.g. ethylene glycol salicylate, menthol, etc.). The addition of the epoxy compound, etc. not only gives excellent cool and refreshing feeling to the skin and high drug action, but also prevents sagging of the gel layer with age and improves the age stability of the effective component. COPYRIGHT: (C)1981,JPO&Japio

Inventors

• 👤 Tatsuo Wada
• 👤 Tetsuo Horiuchi
• 👤 Yusuke Ito
• 👤 Shoichi Tokuda

Bibliographic Details