REAGENT AND METHOD FOR IMMUNOLOGICAL ASSAYING OF ANTIGENS

Abstract

Abstract Translated from French L'INVENTION CONCERNE UN REACTIF POUR UN DOSAGE IMMUNOLOGIQUE D'ANTIGENES, COMPRENANT UN ANTICORPS INSOLUBILISE ET UN ANTICORPS MARQUE, RESPECTIVEMENT PREPARES A PARTIR D'ANTICORPS MONOCLONAUX. LE REACTIF PERMET UNE REDUCTION CONSIDERABLE DU TEMPS DE REACTION SANS NUIRE A LA SENSIBILITE ET A LA PRECISION. ON FOURNIT EGALEMENT UNE METHODE DU SANDWICH PERFECTIONNEE UTILISANT LE REACTIF CI-DESSUS, DANS LAQUELLE L'ANTICORPS INSENSIBILISE ET L'ANTICORPS MARQUE REAGISSENT SIMULTANEMENT AVEC L'ANTIGENE A DOSER. THE INVENTION RELATES TO A REAGENT FOR AN IMMUNOLOGICAL DOSAGE OF ANTIGENS, COMPRISING AN INSOLUBILIZED ANTIBODY AND A TRADEMARK ANTIBODY, RESPECTIVELY PREPARED FROM MONOCLONAL ANTIBODIES. THE REAGENT ALLOWS A CONSIDERABLE REDUCTION OF THE REACTION TIME WITHOUT IMPAIRING SENSITIVITY AND PRECISION. A ADVANCED SANDWICH METHOD USING THE ABOVE REAGENT, IN WHICH THE INSENSITIZED ANTIBODY AND THE BRANDED ANTIBODY REACT SIMULTANEOUSLY WITH THE ANTIGEN TO BE DOSED, IS ALSO PROVIDED.

Inventors

• 👤 Takashi Kudo
• 👤 Toshiyuki Sugawara
• 👤 Ei Mochida

Bibliographic Details