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EP0732106A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Microbubbles containing booster for therapy of disease with ultrasound

Assignee: Individual
•
Filing: 1992-03-19
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Granted: —
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Expires: 2012-03-19
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Abstract

Abstract A booster for treatment of a disease, comprising: an ultrasound source producing ultrasound energy to a fluid that delivers the ultrasound energy to a selected body site; and a sufficient number of microbubbles with a size of 0.1 to 100 µm to reduce a cavitation energy threshold of at least a portion of the fluid and provide a cavitation therapeutic effect.

Inventors

  • 👤 Katsuro Tachibana
  • 👤 Sunro Tachibana

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-10 01:57
CPC Classifications
A; A61; A61K; A61K41/00; A61K41/0028; A61K41/0004; A61K41/0047; A61K49/00; A61K49/22; A61K49/222; A61K49/223; A61K9/00; A61K9/0002; A61K9/0009; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5052

Claims Analysis

Total Claims: 27
Claim 1
Independent Claim 61 words
A booster for treatment of a disease, comprising: an ultrasound source producing ultrasound energy to a fluid that delivers the ultrasound energy to a selected body site; and a sufficient number of microbubbles with a size of 0.1 to 100 µm to reduce a cavitation energy threshold of at least a portion of the fluid and provide a cavitation therapeutic effect.
Claim 2
Dependent Claim 18 words
The booster of claim 1, wherein the cavitation therapeutic effect is a vibration or oscillation of the fluid.
Claim 3
Dependent Claim 14 words
The booster of claim 1, wherein the selected body site is a circulatory vessel.
Claim 4
Dependent Claim 22 words
The booster of claim 1, wherein the selected body site is a lesion formed in a lumenal wall of a circulatory vessel.
Claim 5
Dependent Claim 23 words
The booster of claim 1, wherein the selected body site is a lesion formed adjacent to an interior wall of a circulatory vessel.
Claim 6
Dependent Claim 12 words
The booster of claim 1, wherein the disease is a vascular disease.
Claim 7
Dependent Claim 11 words
The booster of claim 1, wherein the disease is a tumor.
Claim 8
Dependent Claim 10 words
The booster of claim 1, wherein the fluid is blood.
Claim 9
Dependent Claim 12 words
The booster of claim 1, wherein the microbubbles are comprised of gas.
Claim 10
Dependent Claim 12 words
The booster of claim 1, wherein the microbubbles are comprised of liquid.
Claim 11
Dependent Claim 16 words
The booster of claim 1, wherein the fluid is a fluid capable of forming a microbubble.
Claim 12
Dependent Claim 12 words
The booster of claim 1, wherein the fluid is a biological fluid.
Claim 13
Dependent Claim 17 words
The booster of claim 1, wherein the ultrasound source is positioned at an exterior of the body.
Claim 14
Dependent Claim 17 words
The booster of claim 1, wherein the ultrasound source is positioned at an interior of the body.
Claim 15
Dependent Claim 51 words
A booster for treatment of a disease, comprising: an ultrasound source producing ultrasound energy to a fluid that delivers the ultrasound energy to a selected body site; and a sufficient number of microbubbles with a size of 0.1 to 100 µm to provide a sufficient nuclei of cavitation to support cavitation.
Claim 16
Dependent Claim 14 words
The booster of claim 15, wherein the selected body site is a circulatory vessel.
Claim 17
Dependent Claim 22 words
The booster of claim 15, wherein the selected body site is a lesion formed in a lumenal wall of a circulatory vessel.
Claim 18
Dependent Claim 23 words
The booster of claim 15, wherein the selected body site is a lesion formed adjacent to an interior wall of a circulatory vessel.
Claim 19
Dependent Claim 12 words
The booster of claim 15, wherein the disease is a vascular disease.
Claim 20
Dependent Claim 11 words
The booster of claim 15, wherein the disease is a tumor.
Claim 21
Dependent Claim 10 words
The booster of claim 15, wherein the fluid is blood.
Claim 22
Dependent Claim 12 words
The booster of claim 15, wherein the microbubbles are comprised of gas.
Claim 23
Dependent Claim 12 words
The booster of claim 15, wherein the microbubbles are comprised of liquid.
Claim 24
Dependent Claim 16 words
The booster of claim 15, wherein the fluid is a fluid capable of forming a microbubble.
Claim 25
Dependent Claim 12 words
The booster of claim 15, wherein the fluid is a biological fluid.
Claim 26
Dependent Claim 17 words
The booster of claim 15, wherein the ultrasound source is positioned at an exterior of the body.
Claim 27
Dependent Claim 17 words
The booster of claim 15, wherein the ultrasound source is positioned at an interior of the body.

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