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Nucleosides and oligonucleotides containing 2'-ether groups

Assignee: Novartis Pharma GmbH
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Filing: 1995-04-19
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Granted: —
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Expires: 2015-04-19
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Abstract

Abstract Nucleoside 2'-ether derivs. of formula (I) are new. In the formula R1 = H or a protecting gp.; R2 = H, a protecting gp. or a P-contg. nucleotide linking gp.; B = a purine or pyrimidine base or an analogue thereof; R3 = OH, F or R'3; R'3 = 1-8C perfluoro-n-alkyl. Also claimed are oligonucleotide analogues of formula 5'-U-(O-Y-O-V-)x-O-Y-O-W-3' (II) where x = 0-200; Y = a nucleotide linking gp.; U, V and W = natural or synthetic nucleoside units, ≥ 1 of which is of formula (III).

Inventors

  • 👤 Pierre Dr. Martin

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-05 08:20
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; A; A61; A61P; A61P31/00; A61P31/12; A61P35/00; C07H19/16; C07H21/00; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55

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