Patent EP0664122A1 successfully refreshed from Google Patents.
EP0664122A1
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Inhibition of imperfect tissue repair
Assignee: Eli Lilly and Co
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Filing: 1994-12-19
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Granted: —
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Expires: 2014-12-19
Abstract
Abstract A method of inhibiting imperfect tissue repair or a physiological condition due at least in part thereto comprising administering to a human in need thereof an effective amount of a compound having the formula wherein R¹ and R³ are independently hydrogen, -CH₃, wherein Ar is optionally substituted phenyl; R² is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Inventors
- 👤 Thomas Frank Bumol
- 👤 George Joseph Cullinan
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 16:31
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/40; A61K31/4025; A61K31/4523; A61K31/4535; A61P; A61P13/00; A61P13/02; A61P13/12; A61P15/00; A61P17/00; A61P3/00; A61P35/00; A61P43/00; A61P9/00; A61K31/55; C; C07; C07D; C07D409/00; C07D409/02; C07D409/10
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
54 words
The use of a compound having the formula wherein R¹ and R³ are independently hydrogen, -CH₃, or wherein Ar is optionally substituted phenyl; R² is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for inhibiting imperfect tissue repair.
Claim 2
Dependent Claim
13 words
The use of Claim 1 wherein said compound is the hydrochloride salt thereof.
Claim 3
Dependent Claim
13 words
The use of Claim 1 wherein said compound is or its hydrochloride salt.
Claim 4
Dependent Claim
59 words
The use of a compound having the formula wherein R¹ and R³ are independently hydrogen, -CH₃, or wherein Ar is optionally substituted phenyl; R² is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for inhibiting a physiological condition associated with imperfect tissue repair.
Claim 5
Dependent Claim
13 words
The use of Claim 4 wherein said compound is the hydrochloride salt thereof.
Claim 6
Dependent Claim
13 words
The use of Claim 4 wherein said compound is or its hydrochloride salt.
Claim 7
Dependent Claim
95 words
The use of a compound having the formula wherein R¹ and R³ are independently hydrogen, -CH₃, or wherein Ar is optionally substituted phenyl; R² is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for treating the pathological sequelae (complication) or syndromes of diseases or conditions known to initiate imperfect repair of various tissues and organs wherein said diseases or conditions are selected from : infection, chemical or environmental toxic insult, neoplasms, metabolic diseases, heredofamilial diseases, multi-system disease, cardiovascular insult.
Claim 8
Dependent Claim
13 words
The use of Claim 7 wherein said compound is the hydrochloride salt thereof.
Claim 9
Dependent Claim
13 words
The use of Claim 7 wherein said compound is or its hydrochloride salt.
References Cited (Backward Citations)
US4133814A
Cited
US5075321A
Cited
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