Patent EP0650484A1 successfully refreshed from Google Patents.
EP0650484A1
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EP
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Endothelin receptor antagonists
Assignee: SmithKline Beecham Corp
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Filing: 1993-07-15
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Granted: —
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Expires: 2013-07-15
Abstract
Abstract Novel compounds are described which are endothelin receptor antagonists, (I) wherein R1 and R2 are independently (a) or (b); R8 is R1, CO2R7, CO2C(R7)O(CO)XR11, PO3(R7)2, SO2NR7R11, CONR7SO2R11, SO3R7, SO2R7, P(O)(OR7)R7, C=N, NR7SO2R11, C(O)N(R6)2 or tetrazole; R10 is H, phenyl, benzyl, radical (b) imidazolyl, thienyl, furyl, pyrazolyl, isoxazolyl, pyridyl or tetrazolyl eventually substituted. R11 is aryl, cycloalkyl, alk(en)yl, alkynyl and the dotted line indicates the optional presence of a double bond or a pharmaceutically acceptable salt thereof.
Inventors
- 👤 Deborah Lynne Bryan
- 👤 John Duncan Elliot
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-30 22:05
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/06; A; A61; A61P; A61P13/00; A61P13/02; A61P15/00; A61P43/00; A61P9/00; A61P9/12; C07D317/00; C07D317/08; C07D317/44; C07D317/46; C07D317/48; C07D317/50; C07D317/60; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/0803; C07F7/081; C07F7/0812; C07F9/00; C07F9/02; C07F9/547; C07F9/655; C07F9/65515; C07F9/65517
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