EP0503538A1
Expired / Lapsed
EP
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Medicinal composition containing an anthelmintic cyclic depsipeptide
Assignee: Meiji Seika Kaisha Ltd
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Filing: 1992-03-09
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Granted: —
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Expires: 2012-03-09
Abstract
Abstract A medicinal composition comprising a practically water-insoluble anthelmintic compound such as PF1022 substance, which is a cyclic depsipeptide compound, as an active ingredient, and one or more compounds selected from either or both of nonionic surfactants and fats and oils, optionally together with one or more aqueous solvents, wherein the total content of the additives is adjusted to not less than 1 part by weight, preferably from 5 to 50 parts by weight, based on the anthelmintic compound. This composition makes it possible to elevate water-solubility of the anthelmintic comopund and thus enhance its anthelmintic effect.
Inventors
- 👤 Katsuhito c/o MEIJI SEIKA KAISHA LTD. Uomoto
- 👤 Tomoko c/o MEIJI SEIKA KAISHA LTD. Shomura
- 👤 Mitsuyo c/o MEIJI SEIKA KAISHA LTD. Matsumoto
- 👤 Masayuki C/O Meiji Seika Kaisha Ltd. Takagi
- 👤 Takao C/O Meiji Seika Kaisha Ltd. Shimizu
- 👤 Susumu C/O Meiji Seika Kaisha Ltd. Kiriya
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 16:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K31/00; A61K31/33; A61K31/395; A61K47/00; A61K47/06; A61K47/08; A61K47/14; A61K47/44; A61P; A61P33/00; A61P33/10
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
53 words
A medicinal composition comprising (1) 1 part by weight of a compound represented by the following formula or practically water-insoluble anthelmintic analogues thereto as an active ingredient and (2) not less than 1 part by weight of one or more compounds selected from either or both of nonionic surfactants and fats and oils.
Claim 2
Dependent Claim
73 words
A medicinal composition according to claim 1, wherein the nonionic surfactants are selected from glcyerol fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene glycerol fatty acid esters, polyoxyethylene hydrogenated castor oil, lecithin derivatives, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene glycol fatty acid esters, polyoxyethylene castor oil, polyoxyethylene alkyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene lanolin, polyoxyethylene lanolin alcohol, propylene glycol fatty acid esters and polyglycerol fatty acid esters.
Claim 3
Dependent Claim
40 words
A medicinal composition according to claim 1, wherein the fats and oils are selected from almond oil, olive oil, sesame oil, safflower oil, soybean oil, corn oil, rape seed oil, castor oil, cotton seed oil, beef tallow and hardened oils.
Claim 4
Dependent Claim
66 words
A medicinal composition comprising (1) 1 part by weight of a compound represented by the following formula or practically water-insoluble anthelmintic analogues thereto as an active ingredient (2) one or more compounds selected from either or both of nonionic surfactants and fats and oils and (3) one or more aqueous solvents, wherein the total amount of the ingredient (2) and (3) is 1 part by weight.
Claim 5
Dependent Claim
73 words
A medicinal composition according to claim 4, wherein the nonionic surfactants are selected from glcyerol fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene glycerol fatty acid esters, polyoxyethylene hydrogenated castor oil, lecithin derivatives, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene glycol fatty acid esters, polyoxyethylene castor oil, polyoxyethylene alkyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene lanolin, polyoxyethylene lanolin alcohol, propylene glycol fatty acid esters and polyglycerol fatty acid esters.
Claim 6
Dependent Claim
40 words
A medicinal composition according to claim 4, wherein the fats and oils are selected from almond oil, olive oil, sesame oil, safflower oil, soybean oil, corn oil, rape seed oil, castor oil, cotton seed oil, beef tallow and hydrogenated oils.
Claim 7
Dependent Claim
23 words
A medicinal composition according to claim 4, wherein the aqueous solvents are selected from ethylene glycol, propylene glycol, polyethylene glycol, glycerol and N-methyl-2-pyrrolidone.
References Cited (Backward Citations)
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