EP0382173A2
Expired / Lapsed
EP
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PF 1022 substance, method of producing same and anthelmintic composition containing same
Assignee: Meiji Seika Kaisha Ltd
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Filing: 1990-02-06
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Granted: —
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Expires: 2010-02-06
Abstract
Abstract A novel substance having anthelmintic activity, the PF 1022 substance, which is produced by cultivating a fungal strain capable of producing said substance and recovering said substance from the culture.
Inventors
- 👤 Masayuki C/O Meiji Seika Kaisha Ltd. Takagi
- 👤 Tadaaki C/O Meiji Seika Kaisha Ltd. Okada
- 👤 Naotoshi C/O Meiji Seika Kaisha Ltd. Akai
- 👤 Takashi C/O Meiji Seika Kaisha Ltd. Yaguchi
- 👤 Shinji C/O Meiji Seika Kaisha Ltd. Miyadoh
- 👤 Takashi C/O Meiji Seika Kaisha Ltd. Shomura
- 👤 Toru C/O Meiji Seika Kaisha Ltd. Sasaki
- 👤 Masaji C/O Meiji Seika Kaisha Ltd. Sezaki
- 👤 Takao C/O Meiji Seika Kaisha Ltd. Shimizu
- 👤 Masashi C/O Meiji Seika Kaisha Ltd. Niida
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 20:48
CPC Classifications
C; C12; C12P; C12P13/00; C07; C07D; C07D273/00; A; A61; A61P; A61P33/00; A61P33/10; C12P17/00; C12P17/14; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/27
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
6 words
A substance represented by the formula:
Claim 2
Dependent Claim
6 words
A substance represented by the formula:
Claim 3
Dependent Claim
119 words
A substance having the following characteristics: (1) Appearance: Colorless crystals; (2) Melting point: 104-106°C; (3) Molecular formula: C₅₂H₇₆N₄O₁₂; (4) Elemental analysis: (4) Elemental analysis: Calculated (%): C, 65.80; H, 8.07; N, 5.90 Found (%): C, 65.46; H, 8.25; N, 6.10; (5) Mass spectrum (EI-MS): m/z 948 (M⁺); (6) Specific rotation [α] 22 D : -102° (c = 0.1, methanol); (7) Ultraviolet absorption spectrum: As shown in Fig. 1; (8) Infrared absorption spectrum: As shown in Fig. 2; (9) ¹H NMR spectrum: As shown in Fig. 3; (10) ¹³C NMR spectrum: As shown in Fig. 4; (11) Solubility: Soluble in methanol, ethyl acetate, acetone, chloroform and dimethyl sulfoxide; insoluble in water; (12) Classification by basicity, acidity or neutrality: Neutral substance.
Claim 4
Dependent Claim
119 words
A substance having the following characteristics: (1) Appearance: Colorless crystals; (2) Melting point: 104-106°C; (3) Molecular formula: C₅₂H₇₆N₄O₁₂; (4) Elemental analysis: (4) Elemental analysis: Calculated (%): C, 65.80; H, 8.07; N, 5.90 Found (%): C, 65.46; H, 8.25; N, 6.10; (5) Mass spectrum (EI-MS): m/z 948 (M⁺); (6) Specific rotation [α] 22 D : -102° (c = 0.1, methanol); (7) Ultraviolet absorption spectrum: As shown in Fig. 1; (8) Infrared absorption spectrum: As shown in Fig. 2; (9) ¹H NMR spectrum: As shown in Fig. 3; (10) ¹³C NMR spectrum: As shown in Fig. 4; (11) Solubility: Soluble in methanol, ethyl acetate, acetone, chloroform and dimethyl sulfoxide; insoluble in water; (12) Classification by basicity, acidity or neutrality: Neutral substance.
Claim 5
Dependent Claim
41 words
A method of producing the substance of claim 1 or 2 which comprises cultivating a fungal strain capable of producing said substance in a medium thereby producing and accumulating said substance in the culture, and recovering the substance from the culture.
Claim 6
Dependent Claim
20 words
The method according to claim 3, wherein the fungal strain has the characteristics of the strain PF 1022 (FERM BP-2671).
Claim 7
Dependent Claim
19 words
An anthelmintic composition containing the substance of claim 1 or 2 as an active ingredient and a carrier therefor.
Claim 8
Dependent Claim
22 words
The use of the substance of claim 1 or 2 for the manufacture of a medicament for treating and preventing parasitic infection.
References Cited (Backward Citations)
No citation records indexed.
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