EP0482860A1
Expired / Lapsed
EP
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Cosmetic composition
Assignee: Unilever PLC
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Filing: 1991-10-21
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Granted: —
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Expires: 2011-10-21
Abstract
Abstract Novel pseudoceramides are defined, together with their synthesis and compositions comprising them for topical application to human skin, hair and nails
Inventors
- 👤 Peter Critchley
- 👤 Desmond Bernard Hagan
- 👤 Susan Edith Kirsch
- 👤 David Terence Parrott
- 👤 Anthony Vincent Rawlings
- 👤 Ian Richard Scott
- 👤 Anthony Philip Taylor
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-01 23:37
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; C; C07; C07C; C07C235/00; C07C235/02; C07C235/04; C07C235/08; A61K8/68; A61Q; A61Q19/00; A61Q5/00; A61Q19/007; A61Q3/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
235 words
A synthetic pseudoceramide having the structure (2): where R represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 to 49 carbon atoms or the sub-group Y-O-(C a H b )-; R¹ represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 to 28 carbon atoms; R² represents H, a sugar residue, a sulphate residue or a phosphate residue P i ; P i represents the group: R³ represents H, or the sub group (3): X¹, X² and X³ each individually represent H, C₁₋₅ alkyl or C₁₋₅ hydroxyalkyl; Y represents H or a residue or a C₁₄₋₂₂ fatty acid having the structure (4): Z represents -OH -OP i , -OSO₃ ⊖ or an epoxy oxygen, a is an integer of from 7 to 49 b is an integer of from 10 to 98 c is O or an integer of from 1 to 4 d is 0 or 1 x is an integer of from 12 to 20 y is an integer of from 20 to 40 z is O or an integer of from 1 to 4 n is 0 or 1 m is 0 or 1 provided that when the R group has from 9 to 49 carbon atoms, then n + m is 1 or 2.
Claim 2
Dependent Claim
44 words
A synthetic pseudoceramide according to claim 1 in which the group R contains at least 8 carbon atoms or is the subgroup Y-O-(C a H b )-, the group R¹ contains at least 8 carbon atoms and n + m is 1 or 2.
Claim 3
Dependent Claim
68 words
A process for synthesising the pseudoceramide according to claim 1 or claim 2 which comprises the steps of: i. ring opening a terminal epoxide having the formula R¹(CHOR²) n with an amine of formula R³NH₂ to yield the corresponding secondary amine; and ii. acylating the secondary amine with an ester or acid chloride, which ester or acid chloride contains the acyl group R(CHOR²) m to yield the pseudoceramide.
Claim 4
Dependent Claim
42 words
A composition suitable for topical application to skin, hair or nails, which comprises: i. an amount of from 0.0001 to 20% by weight of the pseudoceramide according to claim 1 or claim 2 and ii. a cosmetically acceptable vehicle for the pseudoceramide.
Claim 5
Dependent Claim
42 words
The use of at least 0.0001% by weight of a pseudoceramide according to claim 1 or claim 2 as an agent for skin water barrier repair, in a topical composition comprising a major proportion of a cosmetically acceptable vehicle for the pseudoceramide.
Claim 6
Dependent Claim
24 words
The use of at least 0.0001% by weight of a psuedoceramide according to claim 1 or claim 2 as an agent for improving nails.
Claim 7
Dependent Claim
24 words
The use of at least 0.0001% by weight of a pseudoceramide according to claim 1 or claim 2 as an agent for improving hair.
References Cited (Backward Citations)
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