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Wound dressing and method of preparing the same

Assignee: Duphar International Research BV
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Filing: 1991-02-18
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Granted: —
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Expires: 2011-02-18
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Abstract

Abstract The invention relates to a wound dresssing comprising (1) a lower layer of a hydrogel of a polymer cross-linked under the influence of electron beam (E.B.) radiation, to which optionally one or more medicinal and/or antibacterial agents and/or one or more auxiliary substances have been added, and (2) a polymeric top layer, in which the top layer consists at least substantially of an elastomer selected from the group consisting of a silicone rubber, a polyether-polyurethane copolymer, a polyester-polyurethane copolymer, a polyether-polyester copolymer and an optionally modified block copolymer based on suitable vinyl monomers, and that a fibrous layer is provided between the lower layer and the top layer for bonding the two layers together. The invention further relates to a method of preparing said wound dressing.

Inventors

  • 👤 Wilhelmus E. Hennink
  • 👤 Jacobus J. Zandman
  • 👤 Maria A. E. Van Der Heijden-Van Beek
  • 👤 Hendrik Teunissen

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 16:33
CPC Classifications
A; A61; A61F; A61F13/00; A61F13/02; A61F13/0276; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/24; A61F13/023; A61F2013/00361; A61F2013/00655; A61F2013/00676; A61F2013/0068; A61F2013/00727; A61F2013/00748; A61F2013/00757

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 117 words
A wound dressing comprising (1) a lower layer of a hydrogel of a polymer cross-linked under the influence of electron beam (E.B.) radiation, to which optionally one or more medicinal and/or antibacterial agents and/or one or more auxiliary substances have been added, and (2) a polymeric top layer, which wound dressing is characterised - in that the top layer consists at least substantially of an elastomer selected from the group consisting of a silicone rubber, a polyether-polyurethane copolymer, a polyester-polyurethane copolymer, a polyether-polyester copolymer and an optionally modified block copolymer based on suitable vinylmonomers, and - in that a fibrous layer is provided between the lower layer and the top layer for bonding the two layers together.
Claim 2
Dependent Claim 27 words
A wound dressing as claimed in Claim 1, characterised in that the fibrous layer is an elastic textile layer, preferably a polyester, polyamide or polyurethane fabric (knitting).
Claim 3
Dependent Claim 102 words
A wound dressing as claimed in Claim 1 or 2, characterised - in that the lower layer consists at least substantially of a hydrogel of a polyvinyl alcohol cross-linked under the influence of E.B.-radiation to which optionally one or more medicinal and/or antibacterial agents, in particular silver sulfadiazine,and/or one or more auxiliary substances have been added, - in that the top layer consists of a silicone rubber which has also been cross-linked under the influence of E.B.-radiation, and - in that the fibrous layer for the mutual bonding of the two layers is an elastic textile layer, preferably an elastic fabric (knitting).
Claim 4
Independent Claim 137 words
A method of preparing a wound dressing as claimed in any of the preceding Claims, characterised in that the fibrous layer is provided on a layer of the elastomer which has not yet been cross-linked or is incompletely cross-linked, and that optionally said layer with the fibrous layer provided thereon is then exposed to E.B.-radiation, after which the lower layer is bonded to the fibrous layer by successively providing on the fibrous layer a layer of the hydrogel-forming solution of the polymer to be cross-linked in water, to which solution optionally one or more medicinal and/or antibacterial agents and/or one or more auxiliary substances have been added, and exposing the resulting laminated product to E.B.-radiation, after which optionally another layer of the hydrogel-forming solution is provided and is irradiated until the desired layer thickness has been reached.
Claim 5
Dependent Claim 93 words
A method of preparing a wound dressing as claimed in any of the preceding Claims 1-3, characterised in that successively a layer of the hydrogel-forming solution, to which the agents defined in Claim 4 may have been added, is slightly cured by means of E.B.-radiation to a desired viscosity, a fibrous layer is provided on said layer, and finally, optionally after interim exposure to E.B.-radiation, a layer of the elastomer which has not yet been cross-linked or is incompletely cross-linked is provided thereon, after which the resulting laminated product is exposed to E.B.-radiation.
Claim 6
Dependent Claim 37 words
A method as claimed in Claim 4 or 5, characterised in that silicone rubber is used as an elastomer for the top layer and a solution of polyvinyl alcohol in water is used as the hydrogel-forming solution.
Claim 7
Independent Claim 27 words
A method as claimed in any of the Claims 4-6, characterised in that the resulting wound dressing in a sterile sealing package is finally sterilised by E.B.-radiation.

References Cited (Backward Citations)

FR2392677A1 Cited
FR2542201A1 Cited
EP0305052A1 Cited

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