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Patent EP0445616A2 successfully refreshed from Google Patents.
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EP0445616A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Automatic analysis method and apparatus of the same

Assignee: Hitachi Ltd
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Filing: 1991-02-25
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Granted: —
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Expires: 2011-02-25
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Abstract

Abstract Samples to be analyzed in one operation are contained in sample containers (101). The sample containers are divided into two or more classes of the samples. The samples divided by the classes are accommodated in racks (102), respectively. Marks (201) are put on each rack for identifying the classes of the samples. The marks are read by an automatic reader (106) prior to the starting of the analysis step. The automatic reader also find the order of transfer of the sample containers in each class, which are sent from a transfer line. Analysis parameters of the samples to be analyzed are previously memorized in accompany with the order of the transfer of the sample containers in each class of the samples. When the order of the transfer of the sample containers is discriminated, the analysis parameters are read out from a memory. Selection of a reagent to be dispensed into a reaction containers (108), selection of analysis items, computation of data on a result of the analysis and registering the result of the computation are taken place by an instruction of a control system (105).

Inventors

  • 👤 Takahiro Koakutsu
  • 👤 Yoshio Matsuoka
  • 👤 Tomonori Mimura

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 18:38
CPC Classifications
G; G01; G01N; G01N35/00; G01N35/00584; G01N35/00722; G01N35/00732; B; B01; B01L; B01L9/00; B01L9/06; G01N35/00594; G01N35/00712

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 276 words
An automatic analysis method in which a series of steps are successively performed comprising transferring a plurality of sample containers (101) sequentially in a line, dispensing a sample from the sample containers into reaction containers (108) according to an order of a transfer of the sample containers, dispensing a reagent (110) into the reaction containers, analyzing the sample after a reaction thereof, inputting data on a result of an analysis, computing the data on a basis of predetermined analysis parameters, and storing the result of a computation of the data characterized in that the method comprises steps of accommodating samples to be analyzed in one operation of the analysis to said sample containers dividing into classes which belong to same kinds, respectively, putting marks representative of said classes of said samples on racks (102) each holding a class of sample containers by kind, reading said marks by an automatic reader prior to a starting of analysis processes of said samples and distinguishing an order of a transfer of said classes of said sample containers sent by a transfer line on which said racks are mounted, distinguishing in advance whether analysis parameters (S3, S4, S6-8) concerning said samples to be analyzed are stored to a memory (105) with respect to said classes, and reading out said analysis parameters relating to analysises of said samples from said memory after a transfer order of said classes of said sample containers is found, selecting the reagents to be dispensed into said reaction containers based on said analysis parameters, selecting analysis items of said samples, computing said data on the results of the analysises, and registering the results of the computation.
Claim 2
Dependent Claim 25 words
An automatic analysis method according to claim 1, wherein an arrangement order of said sample containers in each class is previously stored in said memory.
Claim 3
Dependent Claim 241 words
An automatic analysis method in which a series of steps are successively performed comprising transferring a plurality of sample containers sequentially in a line, dispensing a sample from the sample containers into reaction containers according to an order of a transfer of the sample containers, dispensing a reagent into the reaction containers, analyzing the sample after a reaction thereof, inputting data on a result of an analysis, computting the data on a basis of predetermined analysis parameters, and storing the result of a computation of the data characterized in that the method comprises steps of accommodating samples to be analyzed in one operation of the analysis to said sample containers, putting identity marks representative of classes which belong to same kinds and series numbers of said samples in each class container to said sample containers, and reading before a sample analyzing process starts said identity marks sequentially by an automatic reader, distinguishing in advance whether analysis parameters concerning said samples to be analyzed are stored to a memory (105) with respect to said classes, and reading out said analysis parameters relating to analysises of said samples from said memory after said identity marks of said sample containers are read out by said automatic reader, selecting the reagents to be dispensed into said reaction containers based on said analysis parameters, selecting analyses items of said samples, computing said data on the results of the analysises, and registering the results of the computation.
Claim 4
Dependent Claim 51 words
An automatic analysis method according to claim 1, wherein said registering of said analysis parameters to said memory is done through a screen of a display (124), and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 5
Dependent Claim 50 words
An automatic analysis method according to claim 2, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 6
Dependent Claim 47 words
An automatic analysis method according to claim 3, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters concerning said samples in each class is done through the screen of said display.
Claim 7
Dependent Claim 240 words
An automatic analysis method in which a series of steps are successively performed comprising transferring a plurality of sample containers, dispensing a sample from the sample containers into reaction containers, dispensing a reagent into the reaction containers, analyzing the sample after a reaction thereof, inputting data on a result of an analysis, computing the data on a basis of predetermined analysis parameters, and storing the result of a computation of the data characterized in that the method comprises steps of dividing samples to be analyzed in one operation of the analysis into classes which belong to same kinds, respectively, and accommodating the samples to a sample disk which has a mark showing a starting position of the analysis processes, reading said mark by an automatic reader prior to a starting of said analysis processes of said samples, distinguishing in advance whether analysis parameters concerning said samples to be analyzed are stored to a memory with respect to said classes, and reading out said analysis parameters relating to the analysises of said samples from said memory after said starting position is distinguished, selecting the reagents to be dispensed into said reaction containers based on said analysis parameters, selecting analysis items of said samples, computing said data on the results of the analysises in an order of the sample which is arranged in said starting position to a next sample arranged on said sample disk, and registering the result of said computation.
Claim 8
Dependent Claim 38 words
An automatic analysis method according to claim 7, wherein transferring of said sample is carried out by means for rotating said sample disk by a distance corresponding to that between neighboring two samples arranged on said sample disk.
Claim 9
Dependent Claim 247 words
An automatic analysis method in which a series of steps are successively performed transferring a plurality of sample containers, dispensing a sample from the sample containers into reaction containers, dispensing a reagent into the reaction containers, analyzing the sample after a reaction thereof, inputting data on a result of an analysis, computing the data on a basis of predetermined analysis parameters, and storing the result of a computation of the data characterized in that the method comprises steps of accommodating samples to be analyzed in one operation of the analysis to a sample disk which has a mark showing a starting position of the analysis processes, reading said mark by an automatic reader prior to a starting of said analysis processes of said samples, distinguishing in advance whether analysis parameters concerning said samples to be analyzed are stored to a memory with respect to classes which belong to same kinds, respectively, and reading out said analysis parameters relating to the analysises of the sample which is accommodated in a position having a position number counted from said mark on said sample disk after said starting position is distinguished, selecting the reagents to be dispensed into said reaction containers based on said analysis parameters, selecting analysis items of said samples, computing said data on the results of the analysises in an order of the sample which is arranged in said starting position to a next sample arranged on said sample disk, and registering the results of said computation.
Claim 10
Dependent Claim 38 words
An automatic analysis method according to claim 9, wherein transferring of said sample is carried out by means for rotating said sample disk by a distance corresponding to that between neighboring two samples arranged on said sample disk.
Claim 11
Dependent Claim 232 words
An automatic analysis method in which a series of steps are successively performed comprising transferring a plurality of sample containers, dispensing a reagent into the reaction containers, analyzing the sample after a reaction thereof, inputting data on a result of an analysis, computing the data on a basis of predetermined analysis parameters, and storing the result of a computation of the data characterized in that the method comprises steps of putting samples to be analyzed in one operation of the analysis into said sample containers and accommodating the sample containers to said sample disk, respectively, putting identity marks representative of classes which belong to same kinds, respectively, and series numbers of said samples in each class container, and reading before a sample analyzing process starts said identity marks sequentially by an automatic reader, distinguishing in advance whether analysis parameters concerning said samples to be analyzed are stored to a memory with respect to said identity marks to a memory with respect to said identity marks, and reading out said analysis parameters relating to analysises of said samples from said memory after said identity marks of said sample containers are read out by said automatic reader, selecting the reagents to be dispensed into said reaction containers based on said analysis parameters, selecting analysis items of said samples, computing said data on the results of the analysises, and registering the results of the computation.
Claim 12
Dependent Claim 50 words
An automatic analysis method according to claim 7, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 13
Dependent Claim 50 words
An automatic analysis method according to claim 8, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 14
Dependent Claim 50 words
An automatic analysis method according to claim 9, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 15
Dependent Claim 50 words
An automatic analysis method according to claim 11, wherein said registering of said analysis parameters to said memory is done through a screen of a display, and said registering of said analysis parameters to said memory concerning said samples in each class is done through the screen of said display.
Claim 16
Dependent Claim 384 words
An automatic analysis apparatus which calculates analyzed data of each sample based on predetermined analysis parameters characterized in that the apparatus comprises a sample container transferring means (103) for feeding a plurality of sample containers intermittently in a line, a sample dispenser (113) for dispensing the sample in said sample containers transferred sequentially into each of reaction containers (107), a group of reagent containers (109) holding reagents which correspond to analysis items of samples having two or more kinds of classes to be analyzed, a reagent dispenser (114) for selecting a corresponding relative reagent from reagent containers and dispensing a selected reagent into said reaction containers, an analyzer (116) for analyzing said samples in said reaction containers after a reagent dispensation operation is completed, a reaction container transferring means (107) for transferring said reaction containers, racks (102) which attach sample class identification marks for accommodating said samples to said sample containers in each group of classes, an automatic reader for reading said sample class identification marks passing through the reader during a transfer of said sample containers, a calculator (105) which calculates analyzed data of each sample based on predetermined analysis parameters, racks (102) attached identification marks representing classes of said samples to said sample containers, and an automatic reader (106) for reading said marks used to identify the class of samples passing said reader in transferring said sample containers, a control means for computing said data from said analyzer on a basis of analysis parameters to obtain analyzed components of said samples, registering results of computation of said data to a memory (105), registering classes of samples to be analyzed and analysis parameters of required analysis items in connection with an order of transfer of said sample containers by class of said sample, and reading out analysis parameters from the memory corresponding to signals concerning the classes from said automatic reader and reading out analysis parameters from the memory corresponding to signals concerning the classes from said automatic reader and the order of transfer of the classes of said sample containers so as to control said sample container transferring means, said sample dispenser, said reagent dispenser and said reaction container transferring means automatically and seqentially, and means for inputting and outputting said analysis parameters through a key board (126) and a display (124).
Claim 17
Dependent Claim 292 words
Automatic analysis apparatus which calculates analyzed data of each sample based on predetermined analysis parameters characterized in that the apparatus comprises a sample container transferring means for feeding a plurality of sample containers intermittently in a line, a sample dispenser for dispensing the sample in said sample containers transferred sequentially into each of reaction containers, a group of reagent containers holding reagents which correspond to analysis items of samples having two or more kinds of classes to be analyzed, a reagent dispenser for selecting a corresponding relative reagent from reagent containers and dispensing a selected reagent into said reaction containers, an analyzer for analyzing said samples in said reaction containers after a reagent dispensation operation is completed, a reaction container transferring means for transferring said reaction containers, racks for accommodating said sample containers attached identity marks (301) representative of classes which belong to same kinds and series numbers of said samples in each class container, an automatic reader for reading said identity marks passing through the reader during a transfer of said sample containers, a control means for computing said data from said analyzer on a basis of analysis parameters to obtain analyzed components of said samples, registering results of computations of said data to a memory, registering classes of samples to be analyzed and analysis parameters of required analysis items in connection with said identity marks of said sample containers, and reading out analysis parameters from the memory corresponding to the reading signals of said identity marks from said automatic reader so as to control said sample container transferring means, said sample dispenser, said reagent dispenser and said reaction container transferring means automatically and sequentially, and means for inputting and outputting said analysis parameters through a key board and a display.
Claim 18
Dependent Claim 44 words
An automatic analysis apparatus according to claim 16, wherein said display has a function of registering the analysis parameters concerning each analysis item about said samples in said sample containers by rewriting the analysis items for every sample container on a same display screen.
Claim 19
Dependent Claim 43 words
An automatic analysis apparatus according to claim 17, wherein said display has registering means which indicates analysis parameters concerning each analysis item about said samples in said sample containers by rewriting the analysis items for every sample container on a same display screen.
Claim 20
Dependent Claim 236 words
An automatic analysis apparatus which calculates analyzed data of each sample based on predetermined analysis parameters characterized in that the apparatus comprises a sample disk (102) which accommodates samples in sample containers thereon, is rotated intermittently and is attached a mark thereon corresponding to analysis process starting position of the samples a sample dispenser for dispensing the sample in said sample containers into each of reaction containers, a group of reagent containers holding reagents which correspond to analysis items of samples having two or more kinds of classes to be analyzed, a reagent dispenser for selecting a corresponding relative reagent from reagent containers and dispensing a selected reagent into said reaction containers, an analyzer for analyzing said samples in said reaction containers after a reagent dispensation operation is completed, a reaction container transferring means for transferring said reaction containers, an automatic reader for reading said marks passing through the reader during a transfer of said sample containers, a control means for computing said data from said analyzer on a basis of analysis parameters to obtain analyzed components of said samples, registering results of computations of said data to a memory, and reading out analysis parameters from the memory so as to control said sample disk, said sample dispenser, said reagent dispenser and said reaction container transferring means automatically and sequentially, and means for inputting and outputting said analysis parameters through a key board and a display.
Claim 21
Dependent Claim 273 words
An automatic analysis apparatus which calculates analyzed data of each sample based on predetermined analysis parameters characterized in that the apparatus comprises a sample disk which accommodates samples in sample containers attached identity marks relating to classes of said samples and numbers of said sample containers and is rotated intermittently, a sample dispenser for dispensing the sample in said sample containers into each of reaction containers, a group of reagent containers holding reagents which correspond to analysis items of samples having two or more kinds of classes to be analyzed, a reagent dispenser for selecting a corresponding relative reagent from reagent containers and dispensing a selected reagent into said reaction containers, an analyzer for analyzing said samples in said reaction containers after a reagent dispensation operation is completed, a reaction container transferring means for transferring said reaction containers, an automatic reader for reading said identity marks passing through the reader during a transfer of said sample containers, a control means for computing said data from said analyzer on a basis of analysis parameters to obtain analyzed components of said samples, registering results of computations of said data to a memory, registering classes of samples to be analyzed and analysis parameters of required analysis items in connection with said identity marks of said sample containers, and reading out analysis parameters from the memory corresponding to the reading signals of said identity marks from said automatic reader so as to control said sample disk, said sample dispenser, said reagent dispenser and said reaction container transferring means automatically and sequentially, and means for inputting and outputting said analysis parameters through a key board and a display.
Claim 22
Dependent Claim 44 words
An automatic analysis apparatus according to claim 20, wherein said display has a function of registering the analysis parameters concerning each analysis item about said samples in said sample containers by rewritting the analysis items for every sample container on a same display screen.
Claim 23
Dependent Claim 44 words
An automatic analysis apparatus according to claim 21, wherein said display has a function of registering the analysis parameters concerning each analysis item about said samples in said sample containers by rewriting the analysis items for every sample container on a same display screen.

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