Patent EP0441763A2 successfully refreshed from Google Patents.
EP0441763A2
Expired / Lapsed
EP
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Heparin-binding growth factor
Assignee: Barnes-Jewish Hospital
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Filing: 1991-01-07
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Granted: —
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Expires: 2011-01-07
Abstract
Abstract A novel heparin-binding growth factor of 18.9 kDa mol. wt. is disclosed which is purified from bovine uterus and human placenta and has a unique 25 N-terminal amino acid sequence as follows: <IMAGE>
Inventors
- 👤 Thomas Franklin Deuel
- 👤 Yue-Shen Li
- 👤 Peter Gerard Milner
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-08 03:39
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/475
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
62 words
A purified bovine uterus derived heparin-binding growth factor having the following characteristics: (a) a molecular weight of about 18.9 kDa when analyzed in SDS-PAGE gels under reducing conditions, (b) an amino terminal sequence (c) binds to cation exchange resins and heparin-Sepharose, (d) is stable to acetone precipitation, (e) is labile in acid, and (f) has potent mitogenic activity toward NIH 3T3 fibroblasts.
Claim 2
Dependent Claim
17 words
A human placenta derived heparin-binding growth factor of 168 amino acids having the following amino acid sequence:
Claim 3
Dependent Claim
17 words
A bovine uterus derived heparin-binding growth factor of 168 amino acids having the following amino acid sequence:
Claim 4
Dependent Claim
23 words
A DNA sequence consisting of a sequence encoding human heparin binding growth factor of 168 amino acids having the following amino acid sequence:
Claim 5
Dependent Claim
12 words
The cDNA of human heparin-binding growth factor having the following nucleotide sequence:
Claim 6
Dependent Claim
23 words
A DNA sequence consisting of a sequence encoding bovine heparin binding growth factor of 168 amino acids having the following amino acid sequence:
Claim 7
Dependent Claim
12 words
The cDNA of bovine heparin-binding growth factor having the following nucleotide sequence:
References Cited (Backward Citations)
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