Patent EP0436203A2 successfully refreshed from Google Patents.
EP0436203A2
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EP
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Percutaneous gel preparation
Assignee: Toa Eiyo Ltd
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Filing: 1990-12-21
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Granted: —
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Expires: 2010-12-21
Abstract
Abstract A percutaneous gel preparation is disclosed, which comprises a substrate having one surface thereof a crosslinked gel layer formed by crosslinking a composition comprising the following ingredients (a) to (c), the weight ratio of the ingredient (b) to the ingredient (c) being from 1.0/0.25 to 1.0/2.0: (a) isosorbide dinitrate; (b) an acrylate polymer; and (c) a liquid ingredient compatible with the ingredient (b).
Inventors
- 👤 Hitoshi Akemi
- 👤 Saburo Otsuka
- 👤 Takashi Kinoshita
- 👤 Yoshifumi Hosaka
- 👤 Yoshihisa Nakano
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 21:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K31/00; A61K31/33; A61K31/335; A61K31/34; A61K9/7061; A61K9/7076
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
61 words
A percutaneous gel preparation comprising a substrate having one surface thereof a crosslinked gel layer formed by crosslinking a composition comprising the following ingredients (a) to (c), the weight ratio of said ingredient (b) to said ingredient (c) being from 1.0/0 25 to 1.0/2.0: (a) isosorbide dinitrate; (b) an acrylate polymer; and (c) a liquid ingredient compatible with said ingredient (b).
Claim 2
Dependent Claim
26 words
A percutaneous gel preparation as claimed in claim 1, wherein said ingredient (b) is an acrylic copolymer obtained by copolymerizing an alkyl (meth)acrylate with (meth)acrylic acid.
Claim 3
Dependent Claim
26 words
A percutaneous gel preparation as claimed in claim 1, wherein the weight ratio of said ingredient (b) to said ingredient (c) is from 1.0/0.4 to 1.0/2.0.
Claim 4
Dependent Claim
26 words
A percutaneous gel preparation as claimed in claim 3, wherein the weight ratio of said ingredient (b) to said ingredient (c) is from 1.0/0.6 to 1.0/1.8.
Claim 5
Dependent Claim
33 words
A percutaneous gel preparation as claimed in claim 1, wherein the content of said isosorbide dinitrate is from 2 to 50% by weight based on the total amount of said crosslinked gel layer.
Claim 6
Dependent Claim
33 words
A percutaneous gel preparation as claimed in claim 5, wherein the content of said isosorbide dinitrate is from 10 to 40% by weight based on the total amount of said crosslinked gel layer.
Claim 7
Dependent Claim
54 words
A percutaneous gel preparation as claimed in claim 1, wherein said composition further comprises a crosslinking agent selected from a trifunctional isocyanate, a metal alcholate, and a metal chelate compound comprising titanium or aluminum in an amount of from 0.01 to 2.0 parts by weight per 100 parts by weight of said acrylate polymer.
Claim 8
Dependent Claim
23 words
A percutaneous gel preparation as claimed in claim 1, wherein the thickness of said crosslinked gel layer is from 10 to 300 µm.
Claim 9
Dependent Claim
23 words
A percutaneous gel preparation as claimed in claim 8, wherein the thickness of said crosslinked gel layer is from 40 to 150 µm.
References Cited (Backward Citations)
No citation records indexed.
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