EP0407028B1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Medicament inhalation device and formulation
Assignee: Fisons Ltd
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Filing: 1990-05-29
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Granted: 1994-09-14
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Expires: 2010-05-29
Abstract
Abstract A device for the administration by inhalation of a medicament in powdered form comprises a medicament reservoir (3) and metering means for dispensing a dose of medicament from the reservoir (3), characterized in that the reservoir (3) comprises a compacted body of powdered medicament (10) and the metering means includes means (11) for abrading the compacted body (10).
Inventors
- 👤 Andrew Reginald Clark
- 👤 John Leck Hart
- 👤 Nicholas Andrew Murray Drought
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 11:16
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0065; A61M2202/00; A61M2202/06; A61M2202/064; A61M2202/066
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
71 words
A device for the administration by inhalation of a medicament in powdered form, comprising a medicament reservoir (3) adapted to receive a compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10), characterized in that the metering means (11) is adapted to abrade a predetermined dose of medicament from the compacted body (10).
Claim 2
Independent Claim
71 words
A device for the administration by inhalation of a medicament in powdered form, comprising a medicament reservoir (3) adapted to receive a compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10), characterized in that the metering means (11) is adapted to abrade a predetermined dose of medicament from the compacted body (10).
Claim 3
Independent Claim
65 words
A device for the administration by inhalation of a medicament in powdered form, comprising a medicament reservoir (3) comprising a compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10), characterized in that the metering means (11) abrades predetermined doses of medicament from the compacted body (10).
Claim 4
Independent Claim
65 words
A device for the administration by inhalation of a medicament in powdered form, comprising a medicament reservoir (3) comprising a compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10), characterized in that the metering means (11) abrades predetermined doses of medicament from the compacted body (10).
Claim 5
Dependent Claim
17 words
A device according to claim 1 or 2, wherein the means for abrading includes a blade (11).
Claim 6
Independent Claim
27 words
A device according to any one of the preceding claims, wherein the compacted body (10) is urged towards the means for abrading (11) by biassing means (13).
Claim 7
Independent Claim
21 words
A device according to any one of the preceding claims, wherein the compacted body of powdered medicament (10) is loosely compacted.
Claim 8
Independent Claim
22 words
A device according to any one of claims 1 to 4, wherein the compacted body of powdered medicament (10) is tightly compacted.
Claim 9
Independent Claim
19 words
A device according to any one of the preceding claims, wherein the active ingredient of the medicament is hygroscopic.
Claim 10
Independent Claim
25 words
A device according to any one of the preceding claims, wherein the active ingredient of the medicament is selected from sodium cromoglycate and nedocromil sodium.
Claim 11
Independent Claim
17 words
A device according to any one of the preceding claims, wherein the medicament includes an inert carrier.
Claim 12
Independent Claim
117 words
A device according to any one of the preceding claims, wherein a metered dose dispensed from the reservoir (3) is deposited in a through-going pathway including a chamber (21) within which entrained medicament may circulate, wherein the inlet (20) from the pathway to the chamber (21) is tangential to the chamber wall and orthogonal to the longitudinal axis of the chamber, and the outlet (23) from the chamber (21) is situated on the longitudinal axis of the chamber so that entrained medicament is preferentially removed through the outlet (23) from the central zone of the chamber (21), the inlet passageway (20) including a venturi (24) adjacent to the junction of the inlet passageway with the chamber (21).
Claim 13
Dependent Claim
108 words
A compacted body of powdered inhalation medicament for administration from an inhalation device comprising a medicament reservoir (3) adapted to receive said compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10); characterised in that the body comprises a loose powder including an active ingredient having a particle size of from 1 to 10 /1.m compressed to form a tightly compacted body, the degree of compaction being sufficient to impart the body with structural integrity such that a plurality of predetermined doses of medicament can be metered therefrom by abrasion.
Claim 14
Dependent Claim
108 words
A compacted body of powdered inhalation medicament for administration from an inhalation device comprising a medicament reservoir (3) adapted to receive said compacted body of powdered medicament (10) and metering means (11) for dispensing medicament from the reservoir (3), the metering means including means for abrading the compacted body (10); characterised in that the body comprises a loose powder including an active ingredient having a particle size of from 1 to 10 /1.m compressed to form a tightly compacted body, the degree of compaction being sufficient to impart the body with structural integrity such that a plurality of predetermined doses of medicament can be metered therefrom by abrasion.
Claim 15
Dependent Claim
43 words
A tightly compacted body of powdered inhalation medicament according to Claim 11 obtainable by applying a pressure of from 30x10 4 to 150x10 4 Nm- 2 to a loose powder comprising an active ingredient having a particle size of from 1 to 10µrn.
Claim 16
Dependent Claim
28 words
A tightly compacted body of powdered inhalation medicament adapted for use in a device as defined in any one of claims 1 to 4 or 6 to 10.
References Cited (Backward Citations)
No citation records indexed.
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