Patent EP0404205A1 successfully refreshed from Google Patents.
EP0404205A1
Expired / Lapsed
EP
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Composition for noninvasive administration of sedatives and analgesics
Assignee: University of Utah Research Foundation Inc
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Filing: 1986-04-25
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Granted: —
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Expires: 2006-04-25
Abstract
Abstract A composition for use in systemically inducing a perdetermined sedative or analgesic effect comprises an effective dose of a potent sedative or analgesic drug in a form capable of being absorbed through mucosal tissue disposed in a soluble matrix material so that matrix dissoves when placed in a patient's mouth and a holder arranged to providee dose to effect administration of the drug by permitting convenient insertion of the matrix into the mouth of the patient and removal when a predetermined sedative or analgesic effect is obtained.
Inventors
- 👤 Theodore H. Stanley
- 👤 Brian Hague
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 19:12
CPC Classifications
A; A23; A23G; A23G3/00; A23G3/34; A23G3/36; A23G3/364; A23G3/368; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/465; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0056; A61P; A61P43/00; A61P9/00; A61P9/06; A61P9/08; A61P9/12; Y; Y10; Y10S; Y10S426/00; Y10S426/801
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
145 words
A composition for use in systemically inducing a predetermined seedative or analgesic effect in a patient, said composition comprising: an effective dose of a potent sedative or analgesic drug in a form capable of being absorbed through mucosal tissue of the mouth, pharynx, and esophagus, and capable of systemically inducing a condition of sedation or analgesia in the patient: a soluble matrix material into which the drug is dispersed substantially uniformly within the matrix so that the drug is released for absorption through mucosal tissue as the matrix dissolves when placed in a patient's mouth: and holder means secured to the drug-containing matrix, said holder means being configured so as to provide for dose-to-effect administration of the drug by permitting convenient insertion of the drug-containing matrix into the mouth of a patient and convenient removal thereof when a predetermined sedative or analgesic effect is obtained.
Claim 2
Dependent Claim
145 words
A composition for use in systemically inducing a predetermined seedative or analgesic effect in a patient, said composition comprising: an effective dose of a potent sedative or analgesic drug in a form capable of being absorbed through mucosal tissue of the mouth, pharynx, and esophagus, and capable of systemically inducing a condition of sedation or analgesia in the patient: a soluble matrix material into which the drug is dispersed substantially uniformly within the matrix so that the drug is released for absorption through mucosal tissue as the matrix dissolves when placed in a patient's mouth: and holder means secured to the drug-containing matrix, said holder means being configured so as to provide for dose-to-effect administration of the drug by permitting convenient insertion of the drug-containing matrix into the mouth of a patient and convenient removal thereof when a predetermined sedative or analgesic effect is obtained.
Claim 3
Dependent Claim
39 words
A composition as claimed in claim 1 wherein the dosage of drug dispersed in the soluble matrix material is in the range of from 1 to 50 times greater than the dosage that would be given by intravenous injection.
Claim 4
Dependent Claim
53 words
A composition as claimed in any one of the preceding claims wherein the drug-containing amtrix includes an inner matrix containing drug in a suitable concentration for maintaining a desired effect, and an outer matrix covering the inner matrix, said outer matrix containing drug in a suitable concentration for rapidly inducing a desired effect.
Claim 5
Dependent Claim
19 words
A composition as claimed in any one of the preceding claims, wherein the soluble matrix is a carbohydrate mass.
Claim 6
Dependent Claim
17 words
A composition as claimed in claim 4 wherein the carbohydrate mass is suitable for use with diabetics.
Claim 7
Dependent Claim
18 words
A composition as claimed in any one of the preceding claims, wherein the holder means is a stick.
Claim 8
Dependent Claim
22 words
A composition as claimed in any one of the preceding claims, wherein the drug-containing matrix is in the form of a lollipop.
References Cited (Backward Citations)
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