Excitatory amino acid antagonists

Claim 1

A pharmaceutical composition containing a compound of the Formula I, wherein X is represented by a C₁₋₄ alkyl, Z is represented by H, C₁₋₄ alkyl, phenyl, substituted phenyl, or an alkylphenyl substituent in which the phenyl ring may be optionally substituted; R is represented by a substituent selected from the group consisting of hydrogen, halogen, C₁₋₄ alkyl, C₁₋₄ alkoxy, CF₃, OCF₃, OH, NO₂, and CN; R₁ and R₂ are each independently represented by -OH, -OR₃ in which R₃ is represented by a C₁₋₄ alkyl, phenyl, substituted phenyl or an alkylphenyl substituent in which the phenyl ring may be optionally substituted, NR₄R₅ in which R₄ and R₅ are each independently represented by hydrogen or a C₁₋₄ alkyl, or OCH₂OR₃ in which R₃, is as defined above, the pharmaceutically acceptable basic addition salts thereof; and optionally a pharmaceutically acceptable carrier and/or diluent.