Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
31 words
A purified protein that: (a) has an amino-terminal amino acid sequence comprising: NH₂-Lys-Tyr-Tyr-Asp-Lys-Asp-Tyr (b) has a molecular weight of about 100,000 to about 220,000 daltons (c) is a receptor for TGF-β
Claim 2
Dependent Claim
31 words
A purified protein that: (a) has an amino-terminal amino acid sequence comprising: NH₂-Lys-Tyr-Tyr-Asp-Lys-Asp-Tyr (b) has a molecular weight of about 100,000 to about 220,000 daltons (c) is a receptor for TGF-β
Claim 3
Dependent Claim
6 words
A glycosylated protein of claim 1.
Claim 4
Dependent Claim
6 words
An un-glycosylated protein of claim 1.
Claim 5
Dependent Claim
15 words
The protein of claim 1 or a peptide or fragment thereof that specifically binds TGF-β.
Claim 6
Dependent Claim
12 words
The protein of claim 2 in which the TGF-β is natural TGF-β1.
Claim 7
Dependent Claim
12 words
The protein of claim 2 in which the TGF-β is recombinant TGF-β1.
Claim 8
Dependent Claim
12 words
The protein of claim 2 in which the TGF-β is natural TGF-β2.
Claim 9
Dependent Claim
12 words
The protein of claim 2 in which the TGF-β is recombinant TGF-β2.
Claim 10
Dependent Claim
19 words
The protein of claim 6 having a dissociation constant of about 1 X 10⁻¹²M to about 1 X 10⁻⁹M.
Claim 11
Dependent Claim
31 words
Purified type III TGF-β receptor, obtained by the method comprising: (a) solubilizing membranes from cultured HEPM cells (b) affinity purifying type III TGF-β receptor there from using TGF-β as the ligand.
Claim 12
Dependent Claim
31 words
Purified type III TGF-β receptor, obtained by the method comprising: (a) solubilizing membranes from cultured HEPM cells (b) affinity purifying type III TGF-β receptor there from using TGF-β as the ligand.
Claim 13
Dependent Claim
20 words
A purified protein that: (a) has a molecular weight of about 100,000 to about 220,000 daltons (b) specifically binds TGF-β.
Claim 14
Dependent Claim
20 words
A purified protein that: (a) has a molecular weight of about 100,000 to about 220,000 daltons (b) specifically binds TGF-β.
Claim 15
Dependent Claim
12 words
The protein of claim 11 in which the TGF-β is natural TGF-β1.
Claim 16
Dependent Claim
12 words
The protein of claim 11 in which the TGF-β is recombinant TGF-β1.
Claim 17
Dependent Claim
12 words
The protein of claim 11 in which the TGF-β is natural TGF-β2.
Claim 18
Dependent Claim
12 words
The protein of claim 11 in which the TGF-β is recombinant TGF-β2.
Claim 19
Dependent Claim
19 words
The protein of claim 13 having a dissociation constant of about 1 X 10⁻¹²M to about 1 X 10⁻⁹M.