Patent EP0356060A2 successfully refreshed from Google Patents.
EP0356060A2
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EP
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Wound filling compositions
Assignee: 3M Co
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Filing: 1989-08-07
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Granted: —
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Expires: 2009-08-07
Abstract
Abstract Wound filling compositions containing: (a) chitosan, (b) at least one compatible hydrocolloid material other than chitosan, and (c) water, exhibit a variety of properties desirable for use in filling large wounds such as dermal ulcers, yet do not exhibit syneresis. Preferred compositions exhibit antimicrobial activity, wound heading capability, a viscosity suitable to allow them to be applied to and remain in an open wound, and are able to absorb wound exudate.
Inventors
- 👤 Deral T. C/O Minnesota Mining And Mosbey
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-27 09:14
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0061; A61L26/009; A61L26/0009; A61L26/0023; A61L26/0052; A61L26/008; A61P; A61P17/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
65 words
A wound-filling composition comprising: (a) An amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water wherein said composition is a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
Claim 2
Dependent Claim
65 words
A wound-filling composition comprising: (a) An amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water wherein said composition is a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
Claim 3
Dependent Claim
27 words
A composition according to claim 1 wherein said composition has an initial steady shear viscosity of between about 3 x 10⁴ and about 2 x 10⁵ poise.
Claim 4
Dependent Claim
30 words
A composition according to claim 1 wherein said chitosan is present at a concentration of between about 0.1% and about 10% by weight based on the weight of said composition.
Claim 5
Dependent Claim
32 words
A composition according to claim 1 wherein said hydrocolloid material is present at a total concentration of between about 5% and about 25% by weight based on the weight of said composition.
Claim 6
Dependent Claim
14 words
A composition according to claim 1 wherein said hydrocolloid material comprises a polysaccharide gum.
Claim 7
Dependent Claim
30 words
A composition according to claim 5 wherein said polysaccharide gum is selected from a group consisting of locust bean gum, karaya gum, tragacanth gum, guar gum, and hydroxylpropyl guar gum.
Claim 8
Dependent Claim
14 words
A composition according to claim 1 wherein said composition exhibits absorbancy of wound exudate.
Claim 9
Dependent Claim
28 words
A composition according to claim 7 wherein said composition is able to absorb between about 30% and about 50% of its weight without substantial deterioration of the composition.
Claim 10
Dependent Claim
26 words
A composition according to claim 1 further comprising one or more adjuvants selected from the group consisting of polypropylene glycol, glycerol, and low molecular weight polyols.
Claim 11
Independent Claim
68 words
A method of preparing a wound-filling composition comprising combining: (a) an amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water by forming a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
Claim 12
Independent Claim
68 words
A method of preparing a wound-filling composition comprising combining: (a) an amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water by forming a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
Claim 13
Dependent Claim
78 words
Use in a process of preparing a composition for treating a wound to fill the wound of (a) an amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water wherein said composition is a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
Claim 14
Dependent Claim
78 words
Use in a process of preparing a composition for treating a wound to fill the wound of (a) an amount of chitosan effective to promote healing and/or provide anti-microbial activity, (b) at least one compatible hydrocolloid material, other than chitosan, and (c) water wherein said composition is a homogeneous gel having an initial viscosity suitable to allow it to be applied to and remain in a dermal ulcer, yet said composition is neither formed by nor exhibits syneresis.
References Cited (Backward Citations)
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