Patent EP0349656A1 successfully refreshed from Google Patents.
EP0349656A1
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EP
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Biodegradable and resorbable surgical materials and process for preparation of the same
Assignee: Biomaterials Universe Inc
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Filing: 1988-12-27
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Granted: —
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Expires: 2008-12-27
Abstract
Abstract A surgical material which is dea absorbable in vivo comprising a molecularly of polylactic acid or a copolymer of acid, which has a compression bending strength at to 10 3 to 2.5 x 103 kg/cm 2 , compression bending models of 5 5 102 to 24.0 x 10 2 kg/mm 2 , a crystallinity of 10 to be as determined by densitometry, and a viscosity-average molecular weight of 200,000 or more after melt-molding and which can maintain 80 % or more of the initial strength even after being dipped in physiological saline at 370 for 3 months.
Inventors
- 👤 Suong-Hyu Hyon
- 👤 Yoshito Ikada
- 👤 Yasuo Shikinami
- 👤 Kaoru Tsuta
- 👤 Hidekazu Boutani
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 14:11
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/14; A61L31/148; A61L31/04; A61L31/06
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
113 words
Biodegradable and resorbable surgical materials of molded articles of poly(lactic acid) or copolymers of lactic acid and glycolic acid, characterized in that the articles are molecular- orientated, and having a bending strength of 1.6 x 10 3 to 2.5 x 10 3 kg/cm 2 , a bending modulus of 5.5 x 10 2 to 24.0 x 1 0 2 kg/mm 2 , a crystallinity, determined by density measurement, of 10 to 60 %, and a viscosity average molecular weight measured after melt processing of not less than 200,000, and in that at least 80 % of initial strength of the articles is maintained after dipping in a saline at 37°C for three months.
Claim 2
Dependent Claim
113 words
Biodegradable and resorbable surgical materials of molded articles of poly(lactic acid) or copolymers of lactic acid and glycolic acid, characterized in that the articles are molecular- orientated, and having a bending strength of 1.6 x 10 3 to 2.5 x 10 3 kg/cm 2 , a bending modulus of 5.5 x 10 2 to 24.0 x 1 0 2 kg/mm 2 , a crystallinity, determined by density measurement, of 10 to 60 %, and a viscosity average molecular weight measured after melt processing of not less than 200,000, and in that at least 80 % of initial strength of the articles is maintained after dipping in a saline at 37°C for three months.
Claim 3
Dependent Claim
60 words
A process for preparing biodegradable and resorbable surgical materials, characterized by melt-processing poly(lactic acid) or copolymers range from lactic acid and glycolic acid having a viscosity average molecular weight of 300,000 to 600,000 at a temperature range from their melting point to 220°C. in nitrogen atmosphere under a high pressure, and then stretching the molded articles to induce molecular orientation.
Claim 4
Dependent Claim
60 words
A process for preparing biodegradable and resorbable surgical materials, characterized by melt-processing poly(lactic acid) or copolymers range from lactic acid and glycolic acid having a viscosity average molecular weight of 300,000 to 600,000 at a temperature range from their melting point to 220°C. in nitrogen atmosphere under a high pressure, and then stretching the molded articles to induce molecular orientation.
Claim 5
Dependent Claim
39 words
The process for preparing biodegradable and resorbable surgical materials of Claim 2, characterized in that the stretching procedures are carried out in liquid paraffin or in a silicone oil at a temperature of 60° to 180°C in nitirogen atmosphere.
References Cited (Backward Citations)
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