Patent EP0339905A2 successfully refreshed from Google Patents.
EP0339905A2
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Wound healing compositions containing growth factors and retinoids
Assignee: Ethicon Inc
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Filing: 1989-04-24
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Granted: —
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Expires: 2009-04-24
Abstract
Abstract Wound healing compositions comprise an effective wound healing amount of at least one polypeptide growth factor having human mitogenic or angiogenic activity and at least one retinoid. Methods of using such compositions for increasing the rate of healing a wound are described.
Inventors
- 👤 Warren D. Sheffield
- 👤 James A. Mezick
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 03:32
CPC Classifications
A; A61; A61Q; A61Q19/00; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1808; A61K45/00; A61K45/06; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/67; A61K8/671; A61P; A61P17/00; A61P43/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
61 words
A composition for increasing the rate of healing a wound, comprising: a) an effective wound healing amount of at least one polypeptide growth factor having human mitogenic or angiogenic activity; and b) at least one pharmaceutically acceptable chemical entity which is capable of increasing the number of receptors for the growth factor on the membranes of cells at a wound site.
Claim 2
Dependent Claim
61 words
A composition for increasing the rate of healing a wound, comprising: a) an effective wound healing amount of at least one polypeptide growth factor having human mitogenic or angiogenic activity; and b) at least one pharmaceutically acceptable chemical entity which is capable of increasing the number of receptors for the growth factor on the membranes of cells at a wound site.
Claim 3
Dependent Claim
51 words
The composition of claim 1 wherein the growth factor is selected from the group consisting of epidermal growth factor, transforming growth factor-alpha, transforming growth factor-beta, basic fibroblast growth factor, acidic fibroblast growth factor, nerve growth factor, insulin-like growth factor, platelet derived growth factor, or any biologically active fragment or derivative thereof.
Claim 4
Dependent Claim
13 words
The composition of claim 1, wherein the growth factor is epidermal growth factor.
Claim 5
Dependent Claim
16 words
The composition of any of claims 1 to 3, wherein the chemical entity is a retinoid.
Claim 6
Dependent Claim
18 words
The composition of claim 4, wherein the retinoid is selected from retinol, retinal, all-trans-retinoic acid and 13-cis-retinoic acid.
Claim 7
Dependent Claim
55 words
The use of a polypeptide growth factor having mitogenic or angiogenic activity together with a pharmaceutically acceptable chemical entity which is capable of increasing the number of receptors for the growth factor on the membranes of cells at a wound site, in the manufacture of a medicament for increasing the rate of healing of wounds.
Claim 8
Dependent Claim
55 words
The use of a polypeptide growth factor having mitogenic or angiogenic activity together with a pharmaceutically acceptable chemical entity which is capable of increasing the number of receptors for the growth factor on the membranes of cells at a wound site, in the manufacture of a medicament for increasing the rate of healing of wounds.
References Cited (Backward Citations)
No citation records indexed.
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