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EP0303707A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Optical measurement method and apparatus therefor in automatic analyzer

Assignee: Nittec KK
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Filing: 1988-02-17
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Granted: —
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Expires: 2008-02-17
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Abstract

Abstract In an optical measurement method of an automatic analyzer (A) for performing biochemical analysis and immunological analysis by rotating step-wise a reaction tube holder (2) holding a predetermined number of reaction tubes (1) and measuring optically the state of the chemical reaction between a sample and a reagent inside each reaction tube (1) at an optical measurement position (C), the present invention converts the measuring light λ to a single-wavelength light corresponding to the measurement item by a grating (23) controlled by rotation means (24) for reciprocation and rotation, and the optical transmissivity of the air layer and the reaction solution is measured optically by this single-wavelength light using a so-called 'pre- spectral system In the optical measurement system, the 'pre- spectral system' describe above represents the method which converts measuring light to the single-wavelength light corresponding to the measurement item by a filter and radiates this light before the reaction tube containing the reaction solution (the solution in a state where the sample and the reagent corresponding to the measurement item are undergoing a chemical reaction) reaches the optical measurement position, in order to measure its absorbancy.

Inventors

  • 👤 Koichi Wakatake
  • 👤 Hidehiko Fujioka

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-31 14:54
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/17; G01N21/25; G01N21/251; G01N21/253; G01N35/00; G01N35/02; G01N35/025; G01J; G01J3/00; G01J3/12; G01J3/18; G01N21/31; G01N2021/3129; G01N2021/3133; G01N35/04; G01N2035/0439; G01N2035/0444; G01N21/75; G01N2201/00; G01N2201/04; G01N2201/0415

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 98 words
Method for optical measurement in an automatic analysis apparatus which comprises rotating a reaction vessel holder in which a required number of reaction vessels are holded and optically measuring the state of the chemical reactions of the specimen and the reagent in said respective reaction vessels; the light to be measured being converted to light of a single wavelength corresponding to the test item by means of a grated subjected to reciprocating pivotal contal because of rotation means, and the optical transmittances of the optical layer and the reaction solution being optically measured by said single wave light.
Claim 2
Dependent Claim 98 words
Method for optical measurement in an automatic analysis apparatus which comprises rotating a reaction vessel holder in which a required number of reaction vessels are holded and optically measuring the state of the chemical reactions of the specimen and the reagent in said respective reaction vessels; the light to be measured being converted to light of a single wavelength corresponding to the test item by means of a grated subjected to reciprocating pivotal contal because of rotation means, and the optical transmittances of the optical layer and the reaction solution being optically measured by said single wave light.
Claim 3
Dependent Claim 82 words
A method for optical measurement in an automatic analysis apparatus in accordance with Claim 1 wherein the correction of the brightness of the power source for the measurements of said reaction solution and the correction of the difference in optical transmittances among the reaction vessels are performed based on the optical transmittances measured by said single wavelength light in immediate front of a position at which optical measurement is performed and the optical transmittance of the same reaction vessel containing cleaning water.
Claim 4
Dependent Claim 62 words
A method for optical measurement in an automatic analysis apparatus in accordance with either Claim 1 or Claim 2 wherein said wavelength to be measured is divided into a plurality of groups and the light to be measured which is applied to an optical current/voltage converter device is amplified by amplifiers disposed for every wavelength group thereby being applied to a multiplexer.
Claim 5
Independent Claim 140 words
A device for optical measurement in an automatic analysis apparatus provided with a reaction vessel holder holding a required number of reaction vessels therein, driving means for rotating the reaction vessel holder, and an optical measurement device for measuring the absorbances of the reaction vessels which traverse the position of optical measurement by means of the rotation of said reaction vessel holder; a single wavelength corresponding to the test item being selected by a grating which is subjected to reciprocating pivotal rotation by means of rotation means before the reaction vessels has been irradiated with the light to be measured of said optical measurement device, and the air layer and the reaction vessels being irradiated with the selected single wavelength light thereby comparing the transmittance of said air layer with that of the reaction solution to perform colorimetric, optical measurement.
Claim 6
Independent Claim 140 words
A device for optical measurement in an automatic analysis apparatus provided with a reaction vessel holder holding a required number of reaction vessels therein, driving means for rotating the reaction vessel holder, and an optical measurement device for measuring the absorbances of the reaction vessels which traverse the position of optical measurement by means of the rotation of said reaction vessel holder; a single wavelength corresponding to the test item being selected by a grating which is subjected to reciprocating pivotal rotation by means of rotation means before the reaction vessels has been irradiated with the light to be measured of said optical measurement device, and the air layer and the reaction vessels being irradiated with the selected single wavelength light thereby comparing the transmittance of said air layer with that of the reaction solution to perform colorimetric, optical measurement.
Claim 7
Dependent Claim 72 words
A device for optical measurement in an automatic analysis apparatus in accordance with Claim 4 wherein the correction of the brightness of the light source for the measurements of said reaction solution and the correction of the difference in optical transmittances among the reaction vessels are performed based on the optical transmittance of the air layer measured by said single wavelength light and that of the same reaction vessel containing cleaning watee.
Claim 8
Independent Claim 52 words
A device for optical measurement in accordance with either 4 or 5 wherein the wavelength to be measured is divided a plurality of groups and the light to be measured applied to an optical current/voltage converter means is amplified by amplifiers disposed for every wavelength groups thereby being applied to a multiplexer.
Claim 9
Independent Claim 52 words
A device for optical measurement in accordance with either 4 or 5 wherein the wavelength to be measured is divided a plurality of groups and the light to be measured applied to an optical current/voltage converter means is amplified by amplifiers disposed for every wavelength groups thereby being applied to a multiplexer.

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