Patent EP0280807A1 successfully refreshed from Google Patents.
EP0280807A1
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Hyaluronate or hylan poly(ethylene oxide) mixtures
Assignee: Biomatrix Inc
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Filing: 1987-09-10
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Granted: —
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Expires: 2007-09-10
Abstract
Abstract Disclosed are water-based, viscoelastic compositions comprising a mixture of hyaluronic acid or hylan, or salts thereof, and water soluble poly(ethylene oxides). Also disclosed are cosmetic formulations incorporating said compositions.
Inventors
- 👤 Endre A. Balazs
- 👤 Adolf Leshchiner
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-03 16:30
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/30; A61K47/36; A61K8/00; A61K8/18; A61K8/72; A61K8/73; A61K8/735; A61K8/84; A61K8/86; A61K9/0048; A61Q; A61Q19/00; C; C08; C08L; C08L5/00; C08L5/08
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
54 words
A water-based viscoelastic composition comprising a mixture of a hyaluronate and a linear homopolymer of ethylene oxide in water, characterized in that said hyaluronate has a molecular weight of about 50,000 up to about 1,000,000 and said homopolymer has a molecular weight of from about 1 × 10⁵ up to about 5 × 10⁶.
Claim 2
Dependent Claim
54 words
A water-based viscoelastic composition comprising a mixture of a hyaluronate and a linear homopolymer of ethylene oxide in water, characterized in that said hyaluronate has a molecular weight of about 50,000 up to about 1,000,000 and said homopolymer has a molecular weight of from about 1 × 10⁵ up to about 5 × 10⁶.
Claim 3
Dependent Claim
18 words
A composition according to Claim 1, wherein the hyaluronate is an alkali metal or alkaline earth metal hyaluronate.
Claim 4
Dependent Claim
12 words
A composition according to Claim 2, wherein the hyaluronate is sodium hyaluronate.
Claim 5
Dependent Claim
30 words
A composition according to Claim 2 or Claim 3, wherein the hyaluronate is a pure hyaluronic acid salt or a mixture of hyaluronates with proteins and other naturally occurring substances.
Claim 6
Dependent Claim
40 words
A composition according to any preceding claim, wherein the concentration of each component of the mixture is from about 0.01% to about 2% and the ratio by weight of the hyaluronate to the poly(ethylene oxide) is about 1:50 to 100:1.
Claim 7
Dependent Claim
26 words
A cosmetic formulation comprising from about 0.1 to about 50% by weight of a composition according to any preceding claim in combination with conventional cosmetic ingredients.
Claim 8
Dependent Claim
26 words
A cosmetic formulation according to Claim 6 which is a shaving gel, moisturizing cream, moisturizing hand lotion, or emollient moisturizing cream, or an eye drop formulation.
Claim 9
Dependent Claim
19 words
An eye drop formulation according to Claim 7, and further comprising an effective amount of at least one preservative.
Claim 10
Dependent Claim
27 words
A single dose of the eye drop formulation according to Claim 8, comprising about 0.1 - 0.5 ml of said formulation in a sealed, sterile container therefor.
Claim 11
Dependent Claim
19 words
A water-based viscoelastic composition comprising a mixture of a hylan and a linear homopolymer of ethylene oxide in water.
Claim 12
Dependent Claim
19 words
A water-based viscoelastic composition comprising a mixture of a hylan and a linear homopolymer of ethylene oxide in water.
Claim 13
Dependent Claim
18 words
A composition according to Claim 10, wherein the hylan is an alkali metal or alkaline earth metal hylan.
Claim 14
Dependent Claim
12 words
A composition according to Claim 11, wherein the hylan is sodium hylan.
Claim 15
Dependent Claim
27 words
A composition according to any one of Claims 10-12, wherein the hylan has a molecular weight ranging from about 5 × 10⁵ to about 6 × 10⁶.
Claim 16
Dependent Claim
28 words
A cosmetic formulation comprising from about 0.1 to about 50% by weight of a composition according to any one of Claims 10-13 in combination with conventional cosmetic ingredients.
References Cited (Backward Citations)
FR2094109A7
Cited
FR2478468A1
Cited
EP0138572A2
Cited
GB2160097A
Cited
US4582865A
Cited
GB2172295A
Cited
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