Patent US4579583A successfully refreshed from Google Patents.
Patent EP0251806A2 successfully refreshed from Google Patents.
EP0251806A2
Expired / Lapsed
EP
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Plasminogen activator production
Assignee: Merck and Co Inc
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Filing: 1987-07-03
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Granted: —
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Expires: 2007-07-03
Abstract
Abstract The mitogenic protein acidic fibroblast growth factor, (aFGF), is useful for inducing production of plasminogen activator by vascular endothelial cells and thus adaptable for therapeutic application in thrombotic attacks.
Inventors
- 👤 Kenneth A. Thomas
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 13:03
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1825; A61P; A61P7/00; A61P7/02
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
25 words
A composition comprising acidic fibroblast growth factor (aFGF) and heparin for use in digesting clots and in inducing vascular repair while inhibiting subsequent clot formation.
Claim 2
Dependent Claim
25 words
A composition comprising acidic fibroblast growth factor (aFGF) and heparin for use in digesting clots and in inducing vascular repair while inhibiting subsequent clot formation.
Claim 3
Dependent Claim
21 words
A combination of acidic fibroblast growth factor and heparin for the preparation of a medicament useful in the treatment of thrombosis.
Claim 4
Dependent Claim
21 words
A combination of acidic fibroblast growth factor and heparin for the preparation of a medicament useful in the treatment of thrombosis.
Claim 5
Dependent Claim
17 words
A composition comprising an acidic fibroblast growth factor and heparin for inducing the production of plasminogen activator.
Claim 6
Dependent Claim
17 words
A composition comprising an acidic fibroblast growth factor and heparin for inducing the production of plasminogen activator.
Claim 7
Dependent Claim
27 words
A composition suitable for dissolving existing blood clots and preventing the formation of new clots comprising a therapeutic amount of an acidic fibroblast growth factor and heparin.
Claim 8
Dependent Claim
27 words
A composition suitable for dissolving existing blood clots and preventing the formation of new clots comprising a therapeutic amount of an acidic fibroblast growth factor and heparin.
Claim 9
Dependent Claim
39 words
A composition according to Claim 4 in which the acidic fibroblast growth factor is in the range of 1 µg to 100 mg and heparin is in the range of 0.5 to 10 mg in a milliliter of composition.
References Cited (Backward Citations)
No citation records indexed.
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