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EP0245855A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Sucralfate preparations for application on esophagus mucosa

Assignee: Chugai Pharmaceutical Co Ltd
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Filing: 1987-05-14
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Granted: —
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Expires: 2007-05-14
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Abstract

Abstract A sucralfate preparation in the form of a suspension which is suitable for curing esophagitis or esophageal ulcer and a method of preparation thereof are disclosed. The sucralfate preparation comprises sucralfate suspended in an aqueous solution or aqueous suspension of water-soluble or water-insoluble polymeric substance as a suspending agent or thickening agent and has a viscosity in the range from 1,000 to 5,000 cP. This sucralfate preparation adheres selec­tively to ulcerated or inflammatory sites of the esophageal mucosa and is very effective as a cure for esophagitis or esophageal ulcer.

Inventors

  • 👤 Kouji Ishihara
  • 👤 Toshichika Ogasawara
  • 👤 Kazuo Igusa

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-03 15:13
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K47/00; A61K47/30; A61K47/36; A61K47/38; A61K9/00; A61K9/10; A61P; A61P1/00; A61P1/04

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 20 words
A sucralfate preparation in the form of a suspension having a viscosity of from 1,000 to 5,000 centipoise at 20°C.
Claim 2
Dependent Claim 20 words
A sucralfate preparation in the form of a suspension having a viscosity of from 1,000 to 5,000 centipoise at 20°C.
Claim 3
Dependent Claim 17 words
A sucralfate preparation according to Claim 1 for use in the treatment of inflammations of esophageal mucosa.
Claim 4
Dependent Claim 37 words
A sucralfate preparation according to Claim 1 or 2 wherein said preparation comprises sucralfate suspended in an aqueous solution or suspension of one or more water-­soluble or water-insoluble polymeric substances as a suspending agent or thickening agent.
Claim 5
Dependent Claim 20 words
A sucralfate preparation according to Claim 3 wherein said suspending agent or thickening agent is crystalline cellulose, hydroxyethylcellulose or hydroxypropylmethylcellu­lose.

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