Patent EP0243178A2 successfully refreshed from Google Patents.
EP0243178A2
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A marrow/collagen/mineral matrix for bone defect repair
Assignee: Collagen Aesthetics Inc
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Filing: 1987-04-22
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Granted: —
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Expires: 2007-04-22
Abstract
Abstract A method and composition for repair of bone defects employs a matrix which consists of bone marrow extended and strengthened with a mixture of reconstituted fibrillar collagen and a calcium phosphate mineral.
Inventors
- 👤 Karl A. Piez
- 👤 Jack E. Parr
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 21:16
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3641; A61L27/3645; A61L27/365; A61L27/3604; A61L27/3608; A61L27/40; A61L27/44; A61L27/46
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
47 words
A composition for the repair of defects in stress-bearing or nonstress-bearing bone, which comprises a matrix consisting essentially of autogeneic bone marrow in admixture with a collagen/mineral preparation containing reconstituted fibrillar atelopeptide collagen and a calcium phosphate mineral component. and sufficient fluid to obtain a malleable preparation.
Claim 2
Dependent Claim
47 words
A composition for the repair of defects in stress-bearing or nonstress-bearing bone, which comprises a matrix consisting essentially of autogeneic bone marrow in admixture with a collagen/mineral preparation containing reconstituted fibrillar atelopeptide collagen and a calcium phosphate mineral component. and sufficient fluid to obtain a malleable preparation.
Claim 3
Dependent Claim
15 words
A composition according to claim 1 wherein the matrix is 5-50% autogeneic bone marrow volume.
Claim 4
Dependent Claim
20 words
A composition according to claim 1 or 2 wherein the collagen/mineral preparation is 20-70% mineral and 30-80% fibrillar collagen suspension.
Claim 5
Dependent Claim
21 words
A composition according to any one of the preceding claims wherein the collagen is supplied as a suspension of 30-70 mg/ml.
Claim 6
Dependent Claim
27 words
A composition according to any one of the preceding claims wherein the mineral is selected from HA, TCP, or mixtures thereof having bulk densities of 0.5-3.16 g/cc.
Claim 7
Independent Claim
38 words
A method of preparing a matrix consisting essentially of an autogeneic bone marrow, reconstituted fibrillar atelopeptide collagen and a calcium phosphate mineral component which comprises mixing autogeneic bone marrow with a previously prepared mixture of collagen and mineral.
Claim 8
Independent Claim
38 words
A method of preparing a matrix consisting essentially of an autogeneic bone marrow, reconstituted fibrillar atelopeptide collagen and a calcium phosphate mineral component which comprises mixing autogeneic bone marrow with a previously prepared mixture of collagen and mineral.
Claim 9
Dependent Claim
36 words
A composition according to any one of claims 1 to 5 for use in a method for effecting the repair of defects in stress-bearing or nonstress-bearing bone, which comprises implanting the composition into a bone defect.
References Cited (Backward Citations)
No citation records indexed.
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