Patent EP0242956A1 successfully refreshed from Google Patents.
EP0242956A1
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EP
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Self-contained material mixing apparatus
Assignee: Ivion Corp
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Filing: 1987-02-25
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Granted: —
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Expires: 2007-02-25
Abstract
Abstract A self-contained material mixing apparatus (12) is disclosed that is particularly useful for mixing two substances separately contained in the apparatus (12) until an actuator is moved within the apparatus (12) to cause one of the substances to be brought into contact with the other substance. The apparatus (12) may be embodied as a syringe having a piston (16) therein separating two compartments (18, 19) within the syringe body (14). The piston (16) causes an incompressible substance in the rearward compartment (19) to pass to the forward compartment (18) when the volume of the rearward compartment (19) is reduced, but precludes passage of substances in the forward compartment (18) to the rearward compartment (19). The substances to be ultimately mixed together are separately placed in the compartments (18, 19), which substances can be, for example, a drug and a diluent (one of which is preferably in liquid form). For mixing of the substances, the piston (16) is moved rearwardly in the syringe (12) and this results in incompressible material in the rearward compartment (19) being forced to the fron compartment (18) through the one-way valving provided by the piston (16). After mixing of the substances in the forward compartment (18), the material is discharged from the syringe (12) to a patient by moving the piston (16) forwardly in the syringe (12) to expel the mixture from the syringe (12) through an outlet nozzle located at the front of the syringe (12).
Inventors
- 👤 David Crampton Howson
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 17:54
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/178; A61M5/31; A61M5/315; A61M5/31596; A61M5/3129; A61M5/3137; A61M2005/3139
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
252 words
A mixing apparatus, comprising: a storage receptacle defining a chamber that includes first and second compartments, in use said first compartment having a first substance therein and said second compartment having a second substance therein, said storage receptable having an opening at one portion communicating with said second compartment; movable means within said chamber between said first and second compartments, said movable means including valving means having a substance passing portion angularly oriented with respect to the direction of movement of said movable means within said chamber with said substance passing portion being deflectable due to pressure exerted thereon by said first substance to thereby permit passage of said first substance from said first compartment to said second compartment upon application of pressure to said first substance but precluding passage of said first and second substances from said second compartment to said firest compartment; and actuating means having an elongated portion attached to said movable means and restricted to common movement therewith so that movement of said elongated portion in one longitudinal direction causes movement of said movable means in a first direction to cause pressure to be applied to said first substance so that said first substance is transferred from said first compartment to said second compartment for mixing thereat, and movement of said elongated portion in the other opposite longitudinal direction causes movement of said movable means in a second direction to cause a mixture of said first and second substances to be discharged from said apparatus through said opening.
Claim 2
Dependent Claim
252 words
A mixing apparatus, comprising: a storage receptacle defining a chamber that includes first and second compartments, in use said first compartment having a first substance therein and said second compartment having a second substance therein, said storage receptable having an opening at one portion communicating with said second compartment; movable means within said chamber between said first and second compartments, said movable means including valving means having a substance passing portion angularly oriented with respect to the direction of movement of said movable means within said chamber with said substance passing portion being deflectable due to pressure exerted thereon by said first substance to thereby permit passage of said first substance from said first compartment to said second compartment upon application of pressure to said first substance but precluding passage of said first and second substances from said second compartment to said firest compartment; and actuating means having an elongated portion attached to said movable means and restricted to common movement therewith so that movement of said elongated portion in one longitudinal direction causes movement of said movable means in a first direction to cause pressure to be applied to said first substance so that said first substance is transferred from said first compartment to said second compartment for mixing thereat, and movement of said elongated portion in the other opposite longitudinal direction causes movement of said movable means in a second direction to cause a mixture of said first and second substances to be discharged from said apparatus through said opening.
Claim 3
Dependent Claim
31 words
The apparatus of claim 1 wherein said storage receptacle is a syringe having a body portion forming said chambers, and wherein said movable means is a piston within said body portion.
Claim 4
Dependent Claim
38 words
The apparatus of either claim 1 or 2 wherein said apparatus includes stop means for determining the limit of movement of said movable means for determining the limit of movement of said movable means in said first direction.
Claim 5
Dependent Claim
18 words
The apparatus of claim 3 wherein said stop means precludes movement of said movable means outside said chamber.
Claim 6
Independent Claim
36 words
The device of either of claims 3 or 4 wherein said stop means includes retaining means having aperture means for receiving said actuating means therethrough whereby said movable means may be actuated externally of said syringe.
Claim 7
Independent Claim
80 words
The apparatus of any of claims 1 through 5 wherein said mixing apparatus is for mixing a drug, and wherein at least one of said first and second compartments has said drug therein, whereby said drug is mixed with a substance in the other of said first and second compartments upon movement of said movable means in said one direction, and whereby said drug mixture is expelled from said compartment upon movement of said movable means in said second direction.
Claim 8
Dependent Claim
34 words
The apparatus of claim 6 wherein said drug is in one of a solid state and a liquid state, and wherein said diluent is in the other of said solid state and liquid state.
Claim 9
Dependent Claim
36 words
The apparatus of claim 7 wherein said substance in the other of said first and second compartments is a liquid diluent, and wherein said drug is reconstituted by said mixing prior to delivery from said apparatus.
Claim 10
Independent Claim
80 words
The apparatus of any of claims 2 thorugh 8 wherein said substance passing portion of said movable means of said piston includes annular shoulder means extending from said piston and engaging the wall of said syringe body portion, said shoulder means being formed so that upon movement of the piston in the first direction said first substance in said first compartment can terminate engagement of said shoulder means with said wall means to allow passage of said first substance therebetween.
Claim 11
Dependent Claim
56 words
The apparatus of claim 9 wherein said shoulder means is formed so that upon movement of the piston in the second direction substances in said second compartment cause engagement of said shoulder means with the wall of said syringe body portion to thereby preclude passage of said substances from said second compartment to said first compartment.
Claim 12
Independent Claim
111 words
The apparatus of any of claims 2 through 8 wherein said substance passing portion of said valving means of said piston includes relatively movable elements positioned at one side of said piston, with said piston having apertures communicating therethrough to said relatively movable elements of said valving means whereby said relatively movable elements are separated upon application of pressure to said first substance in said first compartment to allow passage of said first substance through said valving means, and whereby said relatively movable elements are precluded from separating upon application of pressure to substances in said second compartment to preclude passage of substances in said second compartment to said first compartment.
Claim 13
Independent Claim
58 words
The apparatus of any of claims 1 through 11 wherein said elongated portion of said actuating means includes first and second elongated sections and cooperating attachment means mounted at one end of each said section whereby said section not connected to said piston can be replaced with a drive rod adapted to be driven in a predetermined manner.
Claim 14
Dependent Claim
83 words
A syringe comprising a plug or other sealing means sealing the end of the syringe through which the piston rod or drive rod passes to prevent escape of liquid through said end, the piston having one-way valve means to permit liquid flow from an upper chamber between the piston and the sealing means to a lower chamber between the piston and the outlet end of the syringe when the piston is moved upwards but not to permit liquid flow in the opposite direction.
Claim 15
Dependent Claim
83 words
A syringe comprising a plug or other sealing means sealing the end of the syringe through which the piston rod or drive rod passes to prevent escape of liquid through said end, the piston having one-way valve means to permit liquid flow from an upper chamber between the piston and the sealing means to a lower chamber between the piston and the outlet end of the syringe when the piston is moved upwards but not to permit liquid flow in the opposite direction.
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