Patent EP0234938A2 successfully refreshed from Google Patents.
EP0234938A2
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EP
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Application of tetrathiafulvalenes in bioelectrochemical processes
Assignee: Cranfield Biotechnology Ltd
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Filing: 1987-02-26
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Granted: —
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Expires: 2007-02-26
Abstract
Abstract Bioelectrochemical processes use tetrathiafulvalenes (TTF) as a mediator of electron transfer between biological systems and electrodes. Typically it finds use in bioelectrochemical assays, e.g. involving glucose oxidase mediated oxidation of glucose. The TTF may be immobilised on the electrode surface, as may one or more enzymes involved in the process.
Inventors
- 👤 Anthony Peter Francis Turner
- 👤 Stuart P. Hendry
- 👤 Marco F- Cardosi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 19:04
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/004; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
36 words
A bioelectrochemical process involving electron transfer between a redox system and an electrode, characterised in that said electron transfer is mediated by a tetrathiafulvalene, not being an electrically conductive charge-transfer complex with an electron acceptor molecule.
Claim 2
Dependent Claim
36 words
A bioelectrochemical process involving electron transfer between a redox system and an electrode, characterised in that said electron transfer is mediated by a tetrathiafulvalene, not being an electrically conductive charge-transfer complex with an electron acceptor molecule.
Claim 3
Dependent Claim
12 words
A process according to claim l wherein the tetrathiafulvalene is in solution.
Claim 4
Dependent Claim
14 words
A process according to claim l wherein the tetrathiafulvalene is deposited on said electrode.
Claim 5
Dependent Claim
26 words
A process according to any one of the preceding claims wherein said electrode has immobilised on it an oxidoreductase enzyme that takes part in said process.
Claim 6
Dependent Claim
20 words
A process according to claim 4 wherein the enzyme is a glycoprotein immobilised on the electrode via its carbohydrate groups.
Claim 7
Dependent Claim
38 words
A process according to any one of the preceding claims wherein the process involves the oxidation of glucose catalysed by the enzyme glucose oxidase or glucose dehydrogenase or the oxidation of an amino acid by amino acid oxidase.
Claim 8
Dependent Claim
15 words
An assay procedure which comprises a process according to any one of the preceding claims.
Claim 9
Dependent Claim
15 words
An assay procedure according to claim 7 wherein the process comprises an enzyme-labelled affinity reaction.
Claim 10
Dependent Claim
23 words
An electrode for use in a bioelectrochemical process of claim l, said electrode comprising a conductive surface onto which a tetrathiafulvalene is deposited.
Claim 11
Dependent Claim
13 words
l0. An electrode according to claim 9 wherein said conductive surface comprises graphite.
Claim 12
Dependent Claim
21 words
An electrode according to claim 9 or claim l0 wherein the conductive surface also has an oxidoreductase enzyme immobilised on it.
Claim 13
Dependent Claim
23 words
An electrode according to claim ll wherein the enzyme is a glycoprotein and is immobilised on the conductive surface via its carbohydrate groups.
Claim 14
Dependent Claim
15 words
An electrode according to claim ll or claim l2 wherein said enzyme is glucose oxidase.
Claim 15
Dependent Claim
14 words
A bioelectrochemical cell incorporating an electrode of any one of claims 9 to l3.
References Cited (Backward Citations)
No citation records indexed.
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