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EP0233403B1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Photo-labile protecting agents and method

Assignee: Medical Research Council
•
Filing: 1986-11-27
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Granted: 1991-01-02
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Expires: 2006-11-27
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Abstract

No abstract record available.

Inventors

  • 👤 David Rostron Trentham
  • 👤 Gordon Paterson Reid

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 17:18
CPC Classifications
C; C07; C07C; C07C251/00; C07C251/72; C07H; C07H21/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 31 words
A diazo compound having the formula where X is an optionally substituted aromatic group which carries a N0 2 group in the ortho-position and Y is an optionally substituted hydrocarbon group.
Claim 2
Dependent Claim 31 words
A diazo compound having the formula where X is an optionally substituted aromatic group which carries a N0 2 group in the ortho-position and Y is an optionally substituted hydrocarbon group.
Claim 3
Dependent Claim 16 words
A hydrazone compound having the formula where X and Y are as defined in claim 1.
Claim 4
Dependent Claim 14 words
A compound as claimed in claim 1 or claim 2, wherein X is o-nitrophenyl.
Claim 5
Dependent Claim 16 words
A compound as claimed in any one of claims 1 to 3, wherein Y is methyl.
Claim 6
Independent Claim 36 words
A method which comprises reacting an organic compound having a reactive hydrogen atom, or an organic compound in the conjugate base form, with a diazo compound as claimed in any of claims 1, 3 or 4.
Claim 7
Dependent Claim 25 words
A method as claimed in claim 5, wherein the reactive hydrogen atom is part of a group selected from phosphate, thiophosphate, phosphonate, carboxyl, and phenol.
Claim 8
Dependent Claim 22 words
A method as claimed in claim 5 or claim 6, wherein the reaction is performed in a shaken mixed water/organic solvent system.
Claim 9
Independent Claim 17 words
A method which comprises photochemically decomposing the reaction product of any one of claims 5 to 7.
Claim 10
Independent Claim 68 words
A method comprising the steps:- providing a caged organic compound which is the reaction product of an organic comp6und having a reactive hydrogen atom with a diazo compound as claimed in any one of claims 1, 3 or 4. introducing the caged organic compound into a biological system and, photochemically decomposing the caged organic compound so as to form the organic compound in situ in the biological system.
Claim 11
Dependent Claim 76 words
A purification method comprising the steps:- providing a starting mixture containing an organic compound having a reactive hydrogen atom and reacting the said organic compound with a diazo compound as claimed in any one of claims 1, 3 or 4, so as to form a protected compound in the mixture, subjecting the mixture to chromatography and recovering the protected organic compound in purified form, and photochemically decomposing the protected compound and recovering the purified organic compound.

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