Patent EP0204468A2 successfully refreshed from Google Patents.
EP0204468A2
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Membrane
Assignee: University of Manchester
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Filing: 1986-05-22
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Granted: —
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Expires: 2006-05-22
Abstract
Abstract Amembrane for an enzyme-electrode type sensortreated to increase the range of linearity of the sensor response.
Inventors
- 👤 Pankaj Maganlal Vadgama
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-09 19:41
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0093; B01D67/00931; C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/002; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
35 words
A membrane permeable to liquids and solutes which comprises one or more layers of polymeric material and at least one layer in which has been treated with a medium comprising an organosilane having reactive groups.
Claim 2
Dependent Claim
35 words
A membrane permeable to liquids and solutes which comprises one or more layers of polymeric material and at least one layer in which has been treated with a medium comprising an organosilane having reactive groups.
Claim 3
Independent Claim
41 words
A method for treating a membrane which is permeable to liquids and solutes and comprises one or more layers of polymeric material wherein a medium comprising an organosiliane having reactive groups is applied to at least one layer in the membrane.
Claim 4
Independent Claim
41 words
A method for treating a membrane which is permeable to liquids and solutes and comprises one or more layers of polymeric material wherein a medium comprising an organosiliane having reactive groups is applied to at least one layer in the membrane.
Claim 5
Dependent Claim
87 words
A sensor of the enzyme-electrode type which incorporates a membrane permeable to liquids and solutes and comprising an enzyme and one or more layers of polymeric material and having an outer layer capable of being brought into contact with a specimen containing an analyte which is convertible in the presence of the enzyme into a species which can be detected by the sensor wherein said outer layer and/or another layer between it and the enzyme has been treated with a medium comprising an organosilane having reactive groups.
Claim 6
Dependent Claim
87 words
A sensor of the enzyme-electrode type which incorporates a membrane permeable to liquids and solutes and comprising an enzyme and one or more layers of polymeric material and having an outer layer capable of being brought into contact with a specimen containing an analyte which is convertible in the presence of the enzyme into a species which can be detected by the sensor wherein said outer layer and/or another layer between it and the enzyme has been treated with a medium comprising an organosilane having reactive groups.
Claim 7
Dependent Claim
45 words
A sensor according to claim 3 which incorporates a laminated membrane comprising an enzyme-containing layer situated between a first layer of polymeric material and a second layer of polymeric material, the first polymeric layer being between the enzyme-containing layer and an electrode in the sensor.
Claim 8
Dependent Claim
22 words
A sensor according to claim 4 wherein the first polymeric layer of the membrane is formed from polymethyl-methacrylate, cellulose acetate or polyurethane.
Claim 9
Dependent Claim
26 words
A sensor according to claim 4 or claim 5 wherein the second polymeric layer of the membrane is formed from a polycarbonate or a modified cellulose.
Claim 10
Dependent Claim
34 words
A sensor according to any one of claims 4 to 6 wherein the second polymeric layer of the membrane is formed from a porous material having pores of average diameter less than 0.05 microns.
Claim 11
Dependent Claim
36 words
A sensor according to any one of claims 3 to 7 wherein the outer layer and/or another layer between it and the enzyme has been treated with an organosilane having three reactive groups in its molecule.
Claim 12
Dependent Claim
31 words
A sensor according to any one of claims 3 to 7 wherein the outer layer and/or another layer between it and the enzymne has been treated with phenyltrichlorosilane, dimethyldichlorosilane or methyltrichlorosilane.
Claim 13
Independent Claim
92 words
A method for determining an analyte in a specimen which comprises contacting the specimen with the outer layer of a membrane, permeable to liquids and solutes and comprising an enzyme, in the presence of which the analyte is convertable into a species detectable by a sensor which incorporates the membrane, and one or more layers of polymeric material, and measuring the response of the sensor to the species, wherein said outer layer and/or another layer between it and the enzyme has been treated with a medium comprising an organosilane having reactive groups.
Claim 14
Independent Claim
92 words
A method for determining an analyte in a specimen which comprises contacting the specimen with the outer layer of a membrane, permeable to liquids and solutes and comprising an enzyme, in the presence of which the analyte is convertable into a species detectable by a sensor which incorporates the membrane, and one or more layers of polymeric material, and measuring the response of the sensor to the species, wherein said outer layer and/or another layer between it and the enzyme has been treated with a medium comprising an organosilane having reactive groups.
References Cited (Backward Citations)
No citation records indexed.
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