Patent US3717057A successfully refreshed from Google Patents.
Patent EP0181966A1 successfully refreshed from Google Patents.
EP0181966A1
Expired / Lapsed
EP
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Compression-coated dispersible tablets
Assignee: Gist Brocades NV
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Filing: 1984-11-13
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Granted: —
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Expires: 2004-11-13
Abstract
Abstract Tablets which yield a fine dispersion when immersed in water, consisting of a quickly dispersible core containing the active substance or substances, covered by a compression coating which is also quickly dispersible.
Inventors
- 👤 Jan Willem Groenendaal
- 👤 Gerrit Jan Sijbrands
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-08 15:31
CPC Classifications
B; B30; B30B; B30B11/00; B30B11/34; A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0056; A61P; A61P9/00; A61P9/08; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2027; A61K9/205; A61K9/2054; A61K9/28; A61K9/2806; A61K9/2833; A61K9/284; A61K9/286; A61K9/2866
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
34 words
Tablets which yield a fine dispersion when immersed in water, characterised in that a quickly dispersible core containing the active substance or substances, is covered by a compression coating which is also quickly dispersible.
Claim 2
Dependent Claim
34 words
Tablets which yield a fine dispersion when immersed in water, characterised in that a quickly dispersible core containing the active substance or substances, is covered by a compression coating which is also quickly dispersible.
Claim 3
Dependent Claim
17 words
Compression-coated tablets according to claim 1, characterised in that the compression-coating contains one or more disintegrating agents.
Claim 4
Dependent Claim
56 words
Compression-coated tablets according to claim 2, characterised in that the disintegrating agent or agents in the coating are chosen from the group consisting of a. cross-linked polyvinylpyrrolidone b. cross-linked sodium carboxymethylcelluloses c. sodium starch glycollates d. ion-exchange resins e. microcrystalline celluloses f. compressible starches g. starch and modified starches h. alginic acid and derivatives. i. formaldehyde-caseins.
Claim 5
Dependent Claim
15 words
Compression-coated tablets according to claim 3, characterised in that the disintegrating agent is cross-linked polyvinylpyrrolidone.
Claim 6
Dependent Claim
15 words
Compression-coated tablets according to claim 3, characterised in that the disintegrating agent is cross-linked carboxymethylcellulose.
Claim 7
Dependent Claim
16 words
Compression-coated tablets according to claim 3, characterised in that the disintegrating agent is sodium starch glycollate.
Claim 8
Dependent Claim
30 words
Compression-coated tablets according to any of the foregoing claims, characterised in that the active substance or substances are present in the core in a concentration not exceeding 70% by weight.
Claim 9
Dependent Claim
25 words
Compression-coated tablets according to any of the foregoing claims, characterised in that the active substance or substances, when unprotected, are prone to sublimation and/or recrystallisation.
Claim 10
Dependent Claim
17 words
Compression-coated tablets according to claim 8, characterised in that the active substance in the core is cyclandelate.
Claim 11
Dependent Claim
22 words
Compression-coated tablets according to claim 9, characterised in that cyclandelate is present in a dosage of 400 to 1200 mg per tablet.
Claim 12
Dependent Claim
23 words
Compression-coated tablets according to claim 10, characterised in that cyclandelate is present in the core in a dosage of 800 mg per tablet.
Claim 13
Dependent Claim
33 words
Compression-coated tablets according to any of the foregoing claims, characterised in that their outer diameter is about 18 mm, their thickness about 9 mm, and their compressed coating is about 1.5 mm thick.
Claim 14
Dependent Claim
41 words
Process for the preparation of the compression-coated medicinal tablets as described in any of the foregoing claims, characterised by the preparation of a quickly dispersible core, containing the medicament, and covering said core with a compression-coating, which is also quickly dispersible.
References Cited (Backward Citations)
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