Patent EP0179477A2 successfully refreshed from Google Patents.
EP0179477A2
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Fibronectin preparations
Assignee: Green Cross Corp
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Filing: 1985-10-24
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Granted: —
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Expires: 2005-10-24
Abstract
Abstract A fibronectin preparation in the form of an aqueous solution at least upon use is disclosed. The preparation contains at least one member selected from the group consisting of disaccharides. albumin and nonionic surface active agents as a stabilizer. The preparation has improved water-solubility when in use and high stability in an aqueous solution.
Inventors
- 👤 Yutaka Hirao
- 👤 Takao Ohmura
- 👤 Kazuo Takechi
- 👤 Tsunetaka Nakajima
- 👤 Masayuki Nishida
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 20:56
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/30; A61K47/42; A61K38/00; A61K38/16; A61K38/17; A61K38/39; A61K47/06; A61K47/08; A61K47/10; A61K47/26; A61K9/00; A61K9/0012; A61K9/0048
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
42 words
A fibronectin preparation in the form of an aqueous solution at least upon use, which contains fibronectin as an active ingredient and at least one member selected from the group consisting of disaccharides, albumin and nonionic surface active agents as a stabilizer.
Claim 2
Dependent Claim
42 words
A fibronectin preparation in the form of an aqueous solution at least upon use, which contains fibronectin as an active ingredient and at least one member selected from the group consisting of disaccharides, albumin and nonionic surface active agents as a stabilizer.
Claim 3
Dependent Claim
24 words
The fibronectin preparation as claimed in Claim 1, wherein the amount of said fibronectin in an aqueous solution is from 250 to 1,000 µg/mℓ.
Claim 4
Dependent Claim
22 words
The fibronectin preparation as claimed in Claim 1, wherein said disaccharide is selected from the group consisting of sucrose, maltose and lactose.
Claim 5
Dependent Claim
16 words
4 . . The fibronectin preparation as claimed in Claim 3, wherein the disaccharide is sucrose.
Claim 6
Dependent Claim
24 words
The fibronectin preparation as claimed in Claim 1, wherein the amount of said disaccharide in an aqueous solution is from 10 to 50 mg/mt.
Claim 7
Dependent Claim
35 words
The fibronectin preparation as claimed in Claim 1, wherein said nonionic surface active agent is selected from the group consisting of polyalkylene glycols, polyol, fatty acid esters, polyol fatty acid ester-polyoxyalkylene condensates and polyoxyalkylene copolymers.
Claim 8
Dependent Claim
15 words
The fibronectin preparation as claimed in Claim 6, wherein the stabilizer is a polyoxyethylene-polyoxypropylene copolymer.
Claim 9
Dependent Claim
24 words
The fibronectin preparation as claimed in Claim 1, wherein the nonionic surface active agent has an average molecular weight of from 2,000 to 20,000.
Claim 10
Dependent Claim
27 words
The fibronectin preparation as claimed in Claim 1, wherein the amount of said nonionic surface active agent in an aqueous solution is from 20 to 500 µg/mℓ.
Claim 11
Dependent Claim
24 words
The fibronectin preparation as claimed in Claim 1, wherein the amount of said albumin in an aqueous solution is from 50 to 1,000 µg/mℓ.
Claim 12
Dependent Claim
18 words
The fibronectin preparation as claimed in Claim 1, wherein the stabilizer is a combination of sucrose and albumin.
Claim 13
Dependent Claim
18 words
,The fibronectin preparation as claimed in Claim 1, wherein the preparation is in the form of eye drops.
Claim 14
Dependent Claim
15 words
The fibronectin preparation as claimed in Claim 1, wherein said preparation is in lyophilized form.
References Cited (Backward Citations)
No citation records indexed.
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