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EP0175801A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Bactericidal composition for disinfecting a contact lens or other similar products in an aqueous medium

Assignee: Individual
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Filing: 1984-09-24
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Granted: —
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Expires: 2004-09-24
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Abstract

Abstract The invention comprises forming a bactericide having a limited period of bacteriological activity with the bactericide comprising three components including a peroxide, a peroxidase and a source of donor molecules adopted to act-as a substrate for the peroxidase; storing the three components in a nonreacting state to maintain the bactericide inactive and admixing the three components in a liquid carrier to. cause a catalyzed reaction by said peroxidase for generating free radicals from the source of donor molecules and immersing a contact lens into the solution simultaneously with the admixture. The concentration level of the three components should be selected such that a substantial portion of the peroxide is consumed during the catalyzed reaction.

Inventors

  • 👤 Jack Dr. Kessler
  • 👤 Robert S. Dr. Rosenbaum

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-25 17:44
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/0005; C11D3/0078; A; A01; A01N; A01N59/00; A01N63/00; A01N63/50; A61; A61L; A61L12/00; A61L12/08; A61L12/12; A61L12/124; A61L12/126

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 63 words
Combined product for disinfecting a contact lens comprising a bactericide having a limited period of bacteriological activity, said bactericide comprising three components including a peroxide, a peroxidase and a source of predetermined donor molecules adapted to act as a substrate for said peroxidase, stored in a nonreacting state such that said bactericide is rendered inactive, and optionally a liquid carrier for said bactericide.
Claim 2
Dependent Claim 63 words
Combined product for disinfecting a contact lens comprising a bactericide having a limited period of bacteriological activity, said bactericide comprising three components including a peroxide, a peroxidase and a source of predetermined donor molecules adapted to act as a substrate for said peroxidase, stored in a nonreacting state such that said bactericide is rendered inactive, and optionally a liquid carrier for said bactericide.
Claim 3
Dependent Claim 28 words
Combined product as defined in claim 1 wherein said source of donor molecule is selected from the class consisting of iodide salts, tyrosine, phenylalanine, benzoic acid,dehydrophenylalanine and vanillan.
Claim 4
Dependent Claim 51 words
Combined product as defined in anyone of claims 1 and 2 wherein said peroxide is selected from the class consisting of hydrogen peroxide, sodium perborate, methyl peroxide, ethyl peroxide or any compound capable of forming a peroxide which is capable of acting as a substrate for peroxidasein its peroxidative catalytic mechanism.
Claim 5
Dependent Claim 18 words
Combined product as defined in anyone of claims 1 to 3 wherein said peroxidase is harse radish peroxidase.
Claim 6
Dependent Claim 40 words
Combined product as defined in anyone of claims 1 to 4 wherein said components are stored in a dry form such as a powder or in a pill needing only to be dissolved in the liquid carrier to be activated.
Claim 7
Dependent Claim 21 words
Combined product as defined in anyone of claims 1 to 5 wherein said liquid carrier comprises water or a saline solution.
Claim 8
Dependent Claim 67 words
Combined product as defined in anyone of claims 1 to 6 wherein the amount of the three components is selected to offer in the liquid carrier a concentration of said source of donor molecule in a range from 10 micromolar to 100 millimolar; of said peroxide in a range of between 1 millimolar to 1 micromolar. of said peroxidase in a range between 0.00001 and 1-0 mg/ml.
Claim 9
Independent Claim 141 words
A method for disinfecting a contact lens comprising forming a bactericide having a limited period of bacteriological activity, said bactericide comprising three components including a peroxide, a peroxidase and a source of predetermined donor molecules adapted to act as a substrate for said peroxidase, storing said three components in a nonreacting state such that said bactericide is rendered inactive; admixing the three components in a liquid carrier to cause a catalyzed reaction by said peroxidase for generating free radicals from said source of donor molecules; selecting the concentration level of said three components such that a substantial percentage of said peroxide is consumed during said catalyzed reaction; and immersing the contact lens into said solution substantially simultaneous with the admixture of all three components whereby bacteria present on said contact lens will be killed during said limited period of bacteriological activity.
Claim 10
Independent Claim 141 words
A method for disinfecting a contact lens comprising forming a bactericide having a limited period of bacteriological activity, said bactericide comprising three components including a peroxide, a peroxidase and a source of predetermined donor molecules adapted to act as a substrate for said peroxidase, storing said three components in a nonreacting state such that said bactericide is rendered inactive; admixing the three components in a liquid carrier to cause a catalyzed reaction by said peroxidase for generating free radicals from said source of donor molecules; selecting the concentration level of said three components such that a substantial percentage of said peroxide is consumed during said catalyzed reaction; and immersing the contact lens into said solution substantially simultaneous with the admixture of all three components whereby bacteria present on said contact lens will be killed during said limited period of bacteriological activity.
Claim 11
Dependent Claim 31 words
9 . A method as defined in claim 8 wherein the components of the bactericide, the liquid carrier and the concentrations are selected according to anyone of claims 2 to 7.

References Cited (Backward Citations)

US4473550A Cited
EP0082798A2 Cited
EP0110609A1 Cited

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