Patent US4327286A successfully refreshed from Google Patents.
Patent EP0153825A2 successfully refreshed from Google Patents.
EP0153825A2
Expired / Lapsed
EP
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Device for sustained release of active substance
Assignee: BTG International Ltd
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Filing: 1985-02-06
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Granted: —
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Expires: 2005-02-06
Abstract
Abstract A device for the sustained release of active substance comprises a wall (1) defining a cavity for the reception of active substance, the wall being of impermeable material and having one or more ports (2) therethrough. Sections of hydrogel material (3) are within the cavity, the hydrogel, in use, being swollen to cover the ports (2) in the cavity wall. Active ingredient is released from the container only through the hydrogel (3) covering the ports (2). In this way sustained and controlled release of the active substance from the device is obtained.
Inventors
- 👤 Neil Bonnette Graham
- 👤 Ernst Reinhard Huehns
- 👤 Marion E. Mcneill
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-26 06:10
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0092; A61F; A61F6/00; A61F6/06; A61F6/08; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/0034; A61K9/0036; A61M; A61M31/00; A61M31/002; A61M25/00; A61M25/0067
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
82 words
A sustained release device for releasing active substance from a cavity when such cavity contains the active substance through a layer of hydrogel covering at least one port in a wall made of water-impermeable material, wherein the wall defines the cavity for the reception of active substance and the cavity contains at least one body of hydrogel material which hydrogel material when in swollen condition is not contiguous with the entire cavity wall but covers the port or ports in the wall.
Claim 2
Dependent Claim
82 words
A sustained release device for releasing active substance from a cavity when such cavity contains the active substance through a layer of hydrogel covering at least one port in a wall made of water-impermeable material, wherein the wall defines the cavity for the reception of active substance and the cavity contains at least one body of hydrogel material which hydrogel material when in swollen condition is not contiguous with the entire cavity wall but covers the port or ports in the wall.
Claim 3
Dependent Claim
15 words
A device according to claim 1 characterised in that the wall is of flexible material.
Claim 4
Dependent Claim
32 words
A device according to claim 1 or 2 characterised in that the hydrogel material when in swollen condition contacts the cavity wall substantially only in the region of the port or ports.
Claim 5
Independent Claim
34 words
A device according to any one of the preceding claims characterised in that it is in the form of a rechargeable surgical implant device and characterised in that the wall is of self-sealing material.
Claim 6
Independent Claim
55 words
A device according to any one of claims 1 to 3 characterised in that it is in the form of a rechargeable surgical implant device and characterised in that it is provided with at least one releasable seal whereby active substance can be introduced into the cavity when the device is implanted in a patient.
Claim 7
Independent Claim
61 words
A device according to any one of the preceding claims characterised in that it comprises a tube of water-impermeable material, the tube wall having a plurality of ports along its length, which tube contains one or more annular sections of hydrogel material which when in swollen condition covers the ports in the tube wall, the tube being sealed at its ends.
Claim 8
Dependent Claim
23 words
A sustained release device according to any one of the preceding claims characterised in that it has in the cavity thereof active substance.
Claim 9
Dependent Claim
44 words
A device according to claim 7 characterised in that the active substance is present in the device in saturated solution or is present in such amount that on introduction of aqueous medium into the device a saturated solution of the active substance is formed.
References Cited (Backward Citations)
No citation records indexed.
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