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EP0152030A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Adult T cell leukemia virus antigen polypeptide

Assignee: Japanese Foundation for Cancer Research
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Filing: 1985-02-01
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Granted: —
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Expires: 2005-02-01
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Abstract

Abstract Recombinant plasmids are constructed by inserting a DNA fragment containing the env gene of adult T cell leukemia virus into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the gene and to recover the peptide. The antigenic polypeptide encoded by the env gene is useful for detection and diagnosis of adult T cell leukemia.

Inventors

  • 👤 Haruo Sugano
  • 👤 Tetsuro Kuga
  • 👤 Tadatsugu Taniguchi
  • 👤 Mitsuaki Yoshida

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-04 20:17
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; C12; C12N; C12N15/00; C12N15/09; C12N15/63; C12N15/79; C12N15/80; C12N15/81; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/14011; C12N2740/14022

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 19 words
An adult T cell leukemia virus antigen polypeptide encoded by the env gene of adult T cell leukemia virus.
Claim 2
Dependent Claim 19 words
An adult T cell leukemia virus antigen polypeptide encoded by the env gene of adult T cell leukemia virus.
Claim 3
Dependent Claim 19 words
A recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated.
Claim 4
Dependent Claim 19 words
A recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated.
Claim 5
Dependent Claim 15 words
The recombinant plasmid according to claim 2, wherein the recombinant plasmid carries the P-60 promoter.
Claim 6
Dependent Claim 10 words
The recombinant plasmid according to claim 3, which is pATYE307.
Claim 7
Dependent Claim 61 words
A process for producing an adult T cell leukemia virus antigen polypeptide which comprises culturing in a medium a microorganism carrying a recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated, accumulating adult T cell leukemia virus antigen polypeptide encoded by the env gene. in the culture and recovering the peptide therefrom.
Claim 8
Dependent Claim 61 words
A process for producing an adult T cell leukemia virus antigen polypeptide which comprises culturing in a medium a microorganism carrying a recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated, accumulating adult T cell leukemia virus antigen polypeptide encoded by the env gene. in the culture and recovering the peptide therefrom.
Claim 9
Dependent Claim 14 words
The process according to claim 5, wherein the recombinant plasmid carries the P-60 promoter.
Claim 10
Dependent Claim 15 words
. The process according to claim 5, wherein the microorganism belongs to the genus Saccharomyces.
Claim 11
Dependent Claim 13 words
The process according to claim 7, wherein the microorganism belongs to Saccharomyces cerevisiae.
Claim 12
Dependent Claim 12 words
The process according to claim 5, wherein the recombinant plasmid is pATYE307.
Claim 13
Dependent Claim 22 words
A microorganism containing a recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated.
Claim 14
Dependent Claim 22 words
A microorganism containing a recombinant plasmid wherein a DNA fragment containing the env gene of adult T cell leukemia virus is incorporated.
Claim 15
Dependent Claim 14 words
The microorganism according to claim 10, wherein the recombinant plasmid carries the P-60 promoter.
Claim 16
Dependent Claim 13 words
The microorganism according to claim 11, wherein the microorganism belongs to Saccharomyces cerevisiae.

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