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EP0150085A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Dextran hexonic acid derivative, ferric hydroxide complex and method and manufacture thereof

Assignee: Polydex Pharmaceuticals Ltd
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Filing: 1985-01-04
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Granted: —
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Expires: 2005-01-04
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Abstract

Abstract A novel hexonic acid derivative of dextran and a complex thereof with ferric hydroxide which complex is stable and non-toxic and has a high iron content are obtained under carefully controlled conditions by reacting dextran having a molecular weight range between 2000 and 6000 with sodium chlorite; and then reacting with ferric hydroxide to produce the desired complex.

Inventors

  • 👤 Anthony L. Tosoni
  • 👤 Kenneth Coelho
  • 👤 Natu Patel

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-07 21:54
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0009; C08B37/0021; A; A61; A61P; A61P7/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 53 words
A dextran hexonic acid derivative having one or more terminal D-gluconic acid residues obtained by the oxidation of a dextran polymer having an average molecular weight of from about 2000 to 6000 with sodium chlorite at a pH of about 2.5 to 4.5 and at a temperature of about 20 to 30 C.
Claim 2
Dependent Claim 53 words
A dextran hexonic acid derivative having one or more terminal D-gluconic acid residues obtained by the oxidation of a dextran polymer having an average molecular weight of from about 2000 to 6000 with sodium chlorite at a pH of about 2.5 to 4.5 and at a temperature of about 20 to 30 C.
Claim 3
Dependent Claim 18 words
A dextran hexonic acid derivative having at least one terminal unit of the formula structure of D-gluconic acid.
Claim 4
Dependent Claim 18 words
A dextran hexonic acid derivative having at least one terminal unit of the formula structure of D-gluconic acid.
Claim 5
Dependent Claim 11 words
A complex of the product of Claim 1 with ferric hydroxide.
Claim 6
Dependent Claim 56 words
A process for producing a hexonic acid derivative of dextran which comprises oxidizing a dextran polymer having a molecular weight between about 2000 and 6000 with sodium chlorite in aqueous solution at a pH of about 2.5 to 4.5 and at a temperature of about 20 to 30°C and recovering the hexonic acid derivative produced thereby.
Claim 7
Dependent Claim 56 words
A process for producing a hexonic acid derivative of dextran which comprises oxidizing a dextran polymer having a molecular weight between about 2000 and 6000 with sodium chlorite in aqueous solution at a pH of about 2.5 to 4.5 and at a temperature of about 20 to 30°C and recovering the hexonic acid derivative produced thereby.
Claim 8
Dependent Claim 31 words
A process for the production of a ferric hydroxide complex with a dextran hexonic acid derivative which comprises reacting ferric hydroxide with the product produced by the process of Claim 4.

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