Patent EP0141584A2 successfully refreshed from Google Patents.
EP0141584A2
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EP
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Durable controlled release microcapsules
Assignee: Bend Research Inc
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Filing: 1984-10-18
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Granted: —
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Expires: 2004-10-18
Abstract
Abstract Impact-resistant microcapsules for the sustained and controlled release of biologically active ingredients through a surrounding permeable polymeric wall are disclosed wherein the ratio by weight of active ingredient to polymer is from about 4:1 to about 1:4, the polymeric walls having high tensile yield and tensile impact strengths and low nitrogen permeabilities.
Inventors
- 👤 Richard W. Baker
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-28 19:08
CPC Classifications
A; A01; A01N; A01N25/00; A01N25/26; A01N25/28; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5031; B; B01; B01J; B01J13/00; B01J13/02; B01J13/06; B01J13/12; B01J13/125
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
90 words
A controlled release microcapsule comprising a core of active ingredient and a permeable polymer surrounding said core, wherein:- (a) the active ingredient is biologically active, (b) the permeable polymer is thermoplastic and soluble in a common organic solvent, and has a tensile yield strength of more than 9,000 lb/in 2 , a tensile impact strength of more than 70 ft-lb/in 2 and a nitrogen permeability of less than 10-10 em 3 -cm/ c m 2- sec-cmHg, and (c) the core-to-polymer ratio is from about 4:1 to about 1:4 by weight.
Claim 2
Dependent Claim
90 words
A controlled release microcapsule comprising a core of active ingredient and a permeable polymer surrounding said core, wherein:- (a) the active ingredient is biologically active, (b) the permeable polymer is thermoplastic and soluble in a common organic solvent, and has a tensile yield strength of more than 9,000 lb/in 2 , a tensile impact strength of more than 70 ft-lb/in 2 and a nitrogen permeability of less than 10-10 em 3 -cm/ c m 2- sec-cmHg, and (c) the core-to-polymer ratio is from about 4:1 to about 1:4 by weight.
Claim 3
Dependent Claim
48 words
The microcapsule of claim 1 wherein the polymer is selected from polysulfones, polyether sulfones, polyaryl sulfones, polycarbonates, polymethylmethacrylates, poly(styrene-acrylonitriles), polystyrenes, acrylonitrile--butadiene-styrene polymers, polyacrylonitriles, polyvinyl fluorides, polyvinylidene fluorides, polyvinyl chlorides, polyvinylidene chlorides, polyethyleneterephthalates, polybutyleneterephthalates, polyamides, polyamide-imides, polyimides, polyacetals, cellulose esters, polyurethanes, polyarylates, polyaryl ethers, and derivatives or copolymers thereof.
Claim 4
Dependent Claim
32 words
The microcapsule of claim 1 wherein the polymer is:- (i) a polysulfone, polyether sulfone or polyaryl sulfone; (ii) a polycarbonate; (iii) a polymethylmethacrylate; (iv) a poly(styrene-acrylonitrile); or (v) a polyamide or polyamide-imide.
Claim 5
Dependent Claim
26 words
The microcapsule of any one of claims 1 to 3 wherein the active ingredient is selected from pheromones, insecticides, herbicides, fertilizers, pharmaceuticals, deodorants, fragrances, and flavours.
Claim 6
Dependent Claim
20 words
The microcapsule of any one of claims 1 to 3 wherein the active ingredient is a pheromone or an insecticide.
Claim 7
Dependent Claim
20 words
The microcapsule of claim 5 wherein the pheromone is disparlure, gossyplure, virelure, muscalure, grandlure, japonilure, trimedlure, codlure or periplanone B.
Claim 8
Dependent Claim
22 words
The microcapsule of claim 5 wherein the insecticide is naled, dimpylate, propoxur, chlorpyrifos, malathion, methyl parathion, carbaryl, methomyl, permethrin, fenvalerate or dichlorvos.
Claim 9
Dependent Claim
14 words
The microcapsule of any preceding claim, prepared by a solvent-evaporation or phase separation process.
Claim 10
Independent Claim
95 words
A method of producing controlled release microcapsules comprising a core of active ingredient and a permeable polymer shell surrounding said core which method comprises microencapsulating a biologically active ingredient in a shell of'a thermoplastic polymer soluble in common organic solvent, said polymer having a tensile yield strength of more than 9000 Ib/in2, a tensile impact strength of more than 70 ft-1b/in 2 and a nitrogen permeability of less than 1 x 10 -10 em 3 -em/em 2 -sec-emHg, so as to provide microcapsules having a core-to-polymer weight ratio of from about 4:1 to about 1:4.
Claim 11
Independent Claim
95 words
A method of producing controlled release microcapsules comprising a core of active ingredient and a permeable polymer shell surrounding said core which method comprises microencapsulating a biologically active ingredient in a shell of'a thermoplastic polymer soluble in common organic solvent, said polymer having a tensile yield strength of more than 9000 Ib/in2, a tensile impact strength of more than 70 ft-1b/in 2 and a nitrogen permeability of less than 1 x 10 -10 em 3 -em/em 2 -sec-emHg, so as to provide microcapsules having a core-to-polymer weight ratio of from about 4:1 to about 1:4.
Claim 12
Independent Claim
39 words
A method of delivering a biologically active ingredient to a life form to be treated therewith which method comprises applying the active ingredient in the form of a microcapsule as claimed in any one of claims 1 to 8.
References Cited (Backward Citations)
No citation records indexed.
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