EP0122000A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Method of detecting temperature in an object
Assignee: Cincinnati Children's Hospital Medical Center
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Filing: 1984-02-28
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Granted: —
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Expires: 2004-02-28
Abstract
Abstract A method to detect indirectly a temperature of an object employing nuclear magnetic resonance techniques (NMR) The method involves obtaining an NMR spectrum to determine chemical shift, relaxation times, spin-spin couplings or quadrupole couplings for an element of a compound having at least one conformational isomer wherein the compound is influenced by a temperature of the object. <??>The difference between the detected radio frequency signals for the same element, spectral patterns or chemical shifts corresponds to the temperature of the object.
Inventors
- 👤 Jerome L. Ackerman
- 👤 Leland C. Clark Jr.
- 👤 Stephen R. Thomas
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 10:52
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/4804; A; A61; A61K; A61K49/00; A61K49/06; G01K; G01K11/00; G01R33/54; G01R33/56; G01R33/5601; Y; Y10; Y10T; Y10T436/00; Y10T436/24
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
61 words
A method of detecting a temperature in an object comprising subjecting the object to a NMR spectrometer, detecting radio-frequency signals in a spectral pattern derived from an element of a compound having at least one conformational isomer associated with the object wherein the element is influenced by the temperature, and comparing the detected signals as a means to detect the temperature.
Claim 2
Independent Claim
61 words
A method of detecting a temperature in an object comprising subjecting the object to a NMR spectrometer, detecting radio-frequency signals in a spectral pattern derived from an element of a compound having at least one conformational isomer associated with the object wherein the element is influenced by the temperature, and comparing the detected signals as a means to detect the temperature.
Claim 3
Dependent Claim
13 words
A method as claimed in Claim 1 wherein the object is an animal.
Claim 4
Dependent Claim
29 words
A method as claimed in either Claim 1 or 2 wherein the detected signals for the element correspond to spectral positions representative of the conformational isomers of the compound.
Claim 5
Dependent Claim
33 words
A method as claimed in Claim 3 wherein the temperature is determined from spectral positions, spin-lattice relaxation time, spin-spin relaxation time, spin-spin coupling, or quadrupole couplings derived from detected element of the compound.
Claim 6
Independent Claim
14 words
A method as claimed in any preceding claim wherein the detected element is fluorine.
Claim 7
Dependent Claim
19 words
A method as claimed in Claim 5 wherein the the fluorine is derived from a perfluorocarbon or derivative thereof.
Claim 8
Independent Claim
17 words
A method as claimed in any preceding claim wherein the temperature is detected in tissue or blood.
Claim 9
Independent Claim
32 words
A method as claimed in any preceding claim wherein the detected signals for the element in the object influenced by a temperature are determined for at least one region in the object.
Claim 10
Dependent Claim
41 words
A method as claimed in Claim 8 wherein the detected signals for an element in the object influenced by a temperature in at least one region is further processed to reconstruct at least one projection of the temperature in the object.
Claim 11
Dependent Claim
13 words
A method as claimed in Claim 9 wherein the projection is an image.
References Cited (Backward Citations)
No citation records indexed.
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