Patent EP0118913A2 successfully refreshed from Google Patents.
EP0118913A2
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Porphyrin derivatives
Assignee: Individual
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Filing: 1984-03-10
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Granted: —
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Expires: 2004-03-10
Abstract
Abstract Porphyrin derivatives containing a dipyrido[1,2- a:3',2'-' d]imidazole moiety and a porphyrin moiety therein and metal complexes thereof are disclosed. These derivatives possess enhanced oxygen-dependent DNA cleaving ability and are effective as antitumor agents.
Inventors
- 👤 Koichi Prof. Dr. Shudo
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 09:36
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/12; C07D471/14
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
121 words
A porphyrin derivative represented by general formula (I): wherein R 1 represents a lower alkyl group, -CH=CH 2 , -CH 2 CH 2 CO 2 H, a substituted or unsubstituted aryl group; h represents 0 to 8 wherein, when h is not smaller than 2, R 1 each may be the same or different; X represents or -CH 2 CH 2 -; m represents an integer of 2 to 4; n represents 0 to 4; Y represents -(CH 2 ) ℓ - or -CO-(CH 2 ) ℓ -CO- wherein ℓ represents an integer of 2 to 5; R 2 represents H or a lower alkyl group; and k represents an integer of 1 to 4, or a metal complex compound thereof.
Claim 2
Dependent Claim
121 words
A porphyrin derivative represented by general formula (I): wherein R 1 represents a lower alkyl group, -CH=CH 2 , -CH 2 CH 2 CO 2 H, a substituted or unsubstituted aryl group; h represents 0 to 8 wherein, when h is not smaller than 2, R 1 each may be the same or different; X represents or -CH 2 CH 2 -; m represents an integer of 2 to 4; n represents 0 to 4; Y represents -(CH 2 ) ℓ - or -CO-(CH 2 ) ℓ -CO- wherein ℓ represents an integer of 2 to 5; R 2 represents H or a lower alkyl group; and k represents an integer of 1 to 4, or a metal complex compound thereof.
Claim 3
Dependent Claim
39 words
The metal complex compound of a porphyrin derivative represented by general formula (I) as claimed in claim 1 wherein said metal of the metal complex compound is selected from the group consisting of Fe III and Cu II .
Claim 4
Dependent Claim
55 words
The metal complex compound of a porphyrin derivative represented by general formula (I) as claimed in claim 2 wherein h represents 3 to 7, X represents; when X is the substituent -NHCO(CH 2 ) m - is located at the ortho- or para-position; n represents 0 or 3 and, m and k each represents 2.
Claim 5
Dependent Claim
15 words
The porphyrin derivative as claimed in claim 1 which is shown by the following formula:
Claim 6
Dependent Claim
16 words
The metal complex compound as claimed in claim 1 which is shown by the following formula:
Claim 7
Dependent Claim
29 words
The metal complex compound as claimed in claim 1 which is a mixture of formulae (A) and (B) shown below: wherein ℓ represents an integer of 2 to 4.
Claim 8
Dependent Claim
16 words
The metal complex compound as claimed in claim 1 which is represented by the following formula:
Claim 9
Dependent Claim
16 words
The metal complex compound as claimed in claim 1 which is shown by the following formula:
Claim 10
Dependent Claim
16 words
The metal complex compound as claimed in claim 1 which is shown by the following formula:
References Cited (Backward Citations)
No citation records indexed.
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