Patent EP0103991A2 successfully refreshed from Google Patents.
EP0103991A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Analgesic capsule
Assignee: Bristol Myers Squibb Co
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Filing: 1983-08-19
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Granted: —
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Expires: 2003-08-19
Abstract
Abstract An analgesic capsule containing enteric coated aspirin granules and powdered APAP (p-acetylaminophenol).
Inventors
- 👤 Thomas M. Tenzca
- 👤 Mahesh K. Patell
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-03 12:51
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K31/00; A61K31/60; A61K31/618; A61K31/621; A61K9/50; A61K9/5084; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
81 words
As an article of manufacture, a therapeutically effective dose of aspirin ano APAP in capsule form; said dose comprising a therapeutically effective amount of enteric coated aspirin granules and APAP in powdered form; said dose being designed to provide APAP available for immediate absorption into the bloodstream from the stomach and aspirin for delayed absorption into tne bloodstream from the intestines whereby the danger of gastric intolerance due to the presence of aspirin in the stomach is significantly diminished or eliminated.
Claim 2
Dependent Claim
81 words
As an article of manufacture, a therapeutically effective dose of aspirin ano APAP in capsule form; said dose comprising a therapeutically effective amount of enteric coated aspirin granules and APAP in powdered form; said dose being designed to provide APAP available for immediate absorption into the bloodstream from the stomach and aspirin for delayed absorption into tne bloodstream from the intestines whereby the danger of gastric intolerance due to the presence of aspirin in the stomach is significantly diminished or eliminated.
Claim 3
Dependent Claim
44 words
An article of manufacture according to claim 1 in which the aspirin is present in said dose in the range of from 80 mgs..to about 650 mgs. and said APAP is present in tne range of from about 80 mgs. to about 650 mgs.
Claim 4
Dependent Claim
42 words
An article of manufacture according to claim 1 in which the aspirin is present in said dose in the range of from 250 mgs. to 325 mgs. and said APAP is present in the range of from 250 mgs. to 325 mgs.
Claim 5
Dependent Claim
21 words
1, 4. An article of manufacture according to claim/2 or 3 in which said dose takes the form of two capsules.
Claim 6
Dependent Claim
37 words
1, 5. An article of manufacture according to claim/2 or 3 in which said dose takes the form of two capsules, each capsule containing one-half of the aspirin ana one-half of the APAP contained in said dose.
Claim 7
Dependent Claim
44 words
any one of to 5 6.. An article of manufacture according to/claimsl/in which said enteric coating material is a copolymer, anionic in character, based on polymethacrylic acid and polymethacrylic acid esters with a ratio of free carboxyl groups to ester groups of about 1:1.
Claim 8
Dependent Claim
35 words
As an article of manufacture, a hard gelatin capsule containing from about 250 mgs. to about 325 mgs. of enteric coated aspirin granules and from about 250 mgs. to about 325 mgs. of powdered APAP.
Claim 9
Dependent Claim
35 words
As an article of manufacture, a hard gelatin capsule containing from about 250 mgs. to about 325 mgs. of enteric coated aspirin granules and from about 250 mgs. to about 325 mgs. of powdered APAP.
Claim 10
Dependent Claim
32 words
An article of manufacture according to claim 7 in which said hard gelatin capsule contains from about 25D mgs. of enteric coated aspirin granules and from about 250 mgs. of powdered APAP.
Claim 11
Dependent Claim
23 words
An article of manufacture according to claim 8 containing about 325 mgs. of enteric coated aspirin granules and 325 mgs. of powdered APAP.
Claim 12
Dependent Claim
39 words
A process for making an analgesic, which comprises covering aspirin granules with an enteric coating, preparing a mixture of the enterically coated aspirin with powdered APAP, and filling a capsule with a single therapeutically effective dose of the mixture.
Claim 13
Dependent Claim
39 words
A process for making an analgesic, which comprises covering aspirin granules with an enteric coating, preparing a mixture of the enterically coated aspirin with powdered APAP, and filling a capsule with a single therapeutically effective dose of the mixture.
Claim 14
Dependent Claim
27 words
A process for making an analgesic which comprises preparing a mixture of enterically coated aspirin with powdered APAP, and encapsulating a therapeutically effective dose of the mixture.
Claim 15
Dependent Claim
27 words
A process for making an analgesic which comprises preparing a mixture of enterically coated aspirin with powdered APAP, and encapsulating a therapeutically effective dose of the mixture.
Claim 16
Dependent Claim
20 words
A process according to Claim 11 wherein said analgesic is as specified in any one of Claims 1 to 9.
Claim 17
Dependent Claim
17 words
An encapsulated composition according to any one of Claims 1 to 9 for use as an analgesic.
References Cited (Backward Citations)
No citation records indexed.
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