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EP0102458A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Device for measuring of concentration of a low molecular weight compound in a complex medium

Assignee: Gambro Lundia AB
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Filing: 1983-06-06
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Granted: —
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Expires: 2003-06-06
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Abstract

Abstract A device for measuring of the concentration of a low molecular weight compound in a complex medium, comprising a dialyzer (1), and enzyme reactor (2) and a measuring unit (3) in communication with each other through a channel system. The channel system is composed of grooves which are arranged on one side of a base plate (18) and which are covered by one or more plates (16, 17) stacked over ech other. Preferably, the plate (18) is manufactured of rigid material, while the next overlying plate (17) is manufactured of soft material. Upon the soft plate is in turn another plate (16) of rigid material provided, whereby the stack of plates is kept under pressure such that the soft plate (17) is clamped between the two plates of rigid material. Conveniently, the dialyzer, the enzyme reactor and the measuring unit are arranged on the upper side of the overlying plate (16) of rigid material and in communication with the respective groove in the rigid underlying plate (18) via perforating holes in the soft intermediate plate (17) and the overlying plate (16).

Inventors

  • 👤 Jan Seivert Claren
  • 👤 Lars-Göran Olsson
  • 👤 Birger Ragnar Hallberg

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-01 18:21
CPC Classifications
C; C12; C12M; C12M41/00; C12M41/30; C12M41/32; G; G01; G01N; G01N35/00; G01N35/08

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 73 words
A device for measuring of concentration of a low molecular weight compound in a complex medium, comprising a dialyzer (1), an enzyme reactor (2) and a measuring unit (3) in communication with each other through a channel system, characterized in that said channel system is composed of grooves which are arranged on one side of a plate (18) and which are covered by one or more plates (16, 17) stacked over each other.
Claim 2
Independent Claim 73 words
A device for measuring of concentration of a low molecular weight compound in a complex medium, comprising a dialyzer (1), an enzyme reactor (2) and a measuring unit (3) in communication with each other through a channel system, characterized in that said channel system is composed of grooves which are arranged on one side of a plate (18) and which are covered by one or more plates (16, 17) stacked over each other.
Claim 3
Dependent Claim 28 words
A device according to claim 1, characterized in that said plate (18) is manufactured of rigid material, while the next covering plate (17) is manufactured of soft material.
Claim 4
Dependent Claim 27 words
A device according to claim 2, characterized in that the soft plate (17) is arranged between the plate (18) and a top plate (16) of rigid material.
Claim 5
Dependent Claim 58 words
A device according to claim 3, characterized in that said dialyzer (1), enzyme reactor (2) and measuring unit (3) are arranged on the upper side of the palte (16) of rigid material and in communication with the rspective groove in said plate via perforating holes in the soft plate (17) and the overlying plates (16) of rigid material.
Claim 6
Independent Claim 34 words
A device according to any of the preceding claims, characterized in that the stack of plates (16, 17, 18) is clamped under pressure by means of a rivet joint, screw joint or welding joint.
Claim 7
Independent Claim 40 words
A device according to any of claims 2 - 5, characterized in that the soft plate (17) is extending in the form of perforated taps with close fitting into the respective holes of the overlying plate (16) of rigid material.
Claim 8
Independent Claim 43 words
A device according to any of the preceding claims, characterized in that it comprises a temperature sensor (9) arranged between the top plate (16) and the intermediate plate (17) in contact with the dialysate, which is adapted to flow from the dialyzer (1).
Claim 9
Independent Claim 38 words
A device according to any of the preceding claims, characterized in that the channel system is interrupted through a pump segment or tubes (4, 5, 6) arranged over a pump hole (P) through said plates (16, 17, 18).
Claim 10
Independent Claim 38 words
A device according to any of the preceding claims, characterized in that it comprises an deaerator (7) consisting of a hole through the intermediate plate (17) and the top plate (16), which is covered by a hydrophobic membrane.
Claim 11
Independent Claim 70 words
A device according to any of the preceding claims, characterized in that said dialyzer (1) comprises a soft plate (1'a) provided with a channel (1"), and a semipermeable membrane covering said channel, whereby the soft plate and the membrane are clamped between a rigid base plate and a rigid top plate while forming tight flow pathways on each side of the membrane for the complex medium and dialysis solution, respectively.
Claim 12
Dependent Claim 20 words
A device according to claim 10, characterized in that the rigid base plate is part of the rigid plate (16).
Claim 13
Independent Claim 23 words
A device according to any of the preceding claims, characterized in that the enzyme reactor is releasably arranged on the rigid plate (16).

References Cited (Backward Citations)

US3512517A Cited
US3884640A Cited
DE2658101A1 Cited
EP0004760A2 Cited

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