Patent EP0098592A2 successfully refreshed from Google Patents.
EP0098592A2
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EP
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Portable artificial pancreas
Assignee: Astellas Pharma Inc
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Filing: 1983-07-05
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Granted: —
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Expires: 2003-07-05
Abstract
Abstract A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit including a micorcomputerfor calculating the blood sugar value from an output signal from the detecting unit and the dose of the control agent based on the value and controlling the pump of the injection unit in accordance with the result of calculation. An assembly including the blood sugar detecting unit and an assembly including the injection unit and the arithmetic cont rol unit are separate from each other and are individually attached to the body. The output signal of the detecting unit is transmitted to the control unit by radio.
Inventors
- 👤 Motoaki Shichiri
- 👤 Kiyoshi Hattori
- 👤 Taichiro Nishiyama
- 👤 Yasuhiko Shingu
- 👤 Kiyotaka Takagi
- 👤 Mamoru Higuchi
- 👤 Norihiko Okamoto
- 👤 Toshiyuki Okudaira
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 14:42
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/168; A61M5/172; A61M5/1723
Claims Analysis
Total Claims: 31
Claim 1
Independent Claim
165 words
A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit including a microcomputer for calculating the blood sugar value from an output signal from the detecting unit and the dose of the control agent based on the value and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that an assembly including the blood sugar detecting unit and an assembly including the injection unit and the arithmetic control unit are separate from each other and are individually attachable to the body, the output signal of the detecting unit being adapted to be transmitted to the control unit by radio.
Claim 2
Dependent Claim
165 words
A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit including a microcomputer for calculating the blood sugar value from an output signal from the detecting unit and the dose of the control agent based on the value and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that an assembly including the blood sugar detecting unit and an assembly including the injection unit and the arithmetic control unit are separate from each other and are individually attachable to the body, the output signal of the detecting unit being adapted to be transmitted to the control unit by radio.
Claim 3
Dependent Claim
48 words
A portable artificial pancreas as defined in claim 1 wherein the assembly including the blood sugar detecting unit further comprises an arithmetic unit for calculating the blood sugar value from the output signal of the detecting unit and a blood sugar display for showing the result of calculation.
Claim 4
Dependent Claim
102 words
A portable artificial pancreas as defined in claim 1 wherein the injection unit comprises a container for a hypoglycemic agent, a container for a hyperglycemic agent, a feed pump for the hypoglycemic agent and a feed pump for the hyperglycemic agent and is adapted to inject the hypoglycemic agent or the hyperglycemic agent into the living body, and the arithmetic control unit calculates the doses of the hypoglycemic agent and the hyperglycemic agent based on the result of calculation of the blood sugar value and controls the pumps of the injection unit in accordance with the result of calculation of the doses.
Claim 5
Dependent Claim
100 words
A portable artificial pancreas as defined in any one of claims 1 to 3 wherein the electrode means comprises a bar-like anode insulated except at its front end serving as an electrode reaction portion and at its rear end serving as a lead wire connecting portion, and a cylindrical cathode having the anode fixedly provided therein, and the anode is cover over the surface of its front end with a hydrophilic semipermeable membrane permeable to hydrogen peroxide, then with an immobilized glucose oxidase membrane and further with a hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide by lamination.
Claim 6
Dependent Claim
62 words
A portable artificial pancreas as defined in claim 4 wherein the cathode is formed on the outer surface of a cylinder, and the anode is inserted in the cylinder and provided with an insulator fixed at its front end to the front end of the cylinder, the anode and the cathode cylinder being fixed at their rear ends to a plastic plug.
Claim 7
Dependent Claim
53 words
A portable artificial pancreas as defined in claim 5 wherein the anode is a noble metal electrode insulated with glass or plastic except at its front end and rear end, and the cathode is a silver electrode or silver chloride electrode formed on the outer surface of a metal cylinder or plastic tube.
Claim 8
Dependent Claim
23 words
A portable artificial pancreas as defined in claim 4 wherein the hydrophilic semipermeable membrane permeable to hydrogen peroxide is a cellulose acetate film.
Claim 9
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 4 wherein the hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide is a polyurethane film.
Claim 10
Dependent Claim
125 words
A portable artificial pancreas as defined in any one of claims 1 to 3 wherein the feed pump comprises a rotatable roller holder formed with a plurality of circular bores parallel with the axis of its-rotation and equidistantly spaced apart on a circumference centered about the axis of rotation, the roller holder being formed in its outer peripheral side surface with a tube guide groove extending circumferentially thereof and partly positioned in the bores, a plurality of rollers respectively fitted in the bores of the roller holder so as to be rotatable but substantially immovable radially and axially of the holder, and an elastic tube having an intermediate portion reeved around the portions of a predetermined number of the rollers positioned in the gudie groove.
Claim 11
Dependent Claim
53 words
'10. A portable artificial pancreas as defined in claim 9 wherein the circular bores extend through the roller holder in the direction of axis of its rotation, and the roller holder is provided on each of its axially opposite end surfaces with a roller retainer for preventing the axial movement of the rollers.
Claim 12
Dependent Claim
47 words
A portable artificial pancreas as defined in claim 10 wherein the roller holder is in the form of a short solid cylinder, and the tube guide groove is annular and is formed in the outer peripheral side surface of the roller holder over the entire circumference thereof.
Claim 13
Dependent Claim
20 words
A portable artificial pancreas as defined in claim 11 wherein the tube guide groove is substantially semicircular in cross section.
Claim 14
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 11 wherein the roller retainer is in the form of a disk concentric with the roller holder.
Claim 15
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 8 wherein the roller holder is made of polytetrafluoroethylene, and the rollers are made of stainless steel.
Claim 16
Dependent Claim
198 words
A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit including a computer for calculating the blood sugar value from an output signal from the detecting unit and the dose of the control agent based on the value and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that an assembly including the blood sugar detecting unit , an assembly including the injection unit and an assembly including the arithmetic control unit are separate from one another, the assembly including the blood sugar detecting unit and the assembly including the injection unit being individually attachable to the body, the output signal of the detecting unit being adapted to be transmitted to the control unit by radio, the control unit being adapted to transmit a control signal to the injection unit by radio.
Claim 17
Dependent Claim
198 words
A portable artificial pancreas comprising a blood sugar detecting unit including electrode means to be inserted into the living body for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit including a computer for calculating the blood sugar value from an output signal from the detecting unit and the dose of the control agent based on the value and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that an assembly including the blood sugar detecting unit , an assembly including the injection unit and an assembly including the arithmetic control unit are separate from one another, the assembly including the blood sugar detecting unit and the assembly including the injection unit being individually attachable to the body, the output signal of the detecting unit being adapted to be transmitted to the control unit by radio, the control unit being adapted to transmit a control signal to the injection unit by radio.
Claim 18
Dependent Claim
48 words
A portable artificial pancreas as defined in claim 15 wherein the assembly including the blood sugar detecting unit further comprises an arithmetic unit for calculating the blood sugar value from the output signal of the detecting unit and a blood sugar display for showing the result of calculation.
Claim 19
Dependent Claim
102 words
A portable artificial pancreas as defined in claim 15 wherein the injection unit comprises a container for a hypoglycemic agent, a container for a hyperglycemic agent, a feed pump for the hypoglycemic agent and a feed pump for the hyperglycemic agent and is adapted to inject the hypoglycemic agent or the hyperglycemic agent into the living body, and the arithmetic control unit calculates the doses of the hypoglycemic agent and the hyperglycemic agent based on the result of calculation of the blood sugar value and controls the pumps of the injection unit in accordance with the result of calculation of the doses.
Claim 20
Dependent Claim
100 words
A portable artificial pancreas as defined in any one of claims 15 to 17 wherein the electrode means comprises a bar-like anode insulated except at its front end serving as an electrode reaction portion and at its rear end serving as a lead wire connecting portion, and a cylindrical cathode having the anode fixedly provided therein, and the anode is cover over the surface of its front end with a hydrophilic semipermeable membrane permeable to hydrogen peroxide, then with an immobilized glucose oxidase membrane and further with a hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide by lamination.
Claim 21
Dependent Claim
62 words
A portable artificial pancreas as defined in claim 18 wherein the cathode is formed on the outer surface of a cylinder, and the anode is inserted in the cylinder and provided with an insulator fixed at its front end to the front end of the cylinder, the anode and the cathode cylinder being fixed at their rear ends to a plastic plug.
Claim 22
Dependent Claim
53 words
A portable artificial pancreas as defined in claim 19 wherein the anode is a noble metal electrode insulated with glass or plastic except at its front end and rear end, and the cathode is a silver electrode or silver chloride electrode formed on the outer surface of a metal cylinder or plastic tube.
Claim 23
Dependent Claim
23 words
A portable artificial pancreas as defined in claim 18 wherein the hydrophilic semipermeable membrane permeable to hydrogen peroxide is a cellulose acetate film.
Claim 24
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 18 wherein the hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide is a polyurethane film.
Claim 25
Dependent Claim
126 words
A portable artificial pancreas as defined in any one of claims 15 to 17 wherein the feed pump comprises a rotatable roller holder formed with a plurality of circular bores parallel with the axis of its rotation and equidistantly spaced apart on a circumference centered about the axis of rotation, the roller holder being formed in its outer peripheral side surface with a tube guide groove extending circumferentially thereof and partly positioned in the bores, a plurality of rollers respectively fitted in the bores of the roller holder so as to be rotatable but substantially immovable radially and axially of the holder, and an elastic tube having an intermediate portion reeved around the portions of a predetermined number of the rollers positioned in the gudie groove.
Claim 26
Dependent Claim
52 words
A portable artificial pancreas as defined in claim 23 wherein the circular bores extend through the roller holder in the direction of axis of its rotation, and the roller holder is provided on each of its axially opposite end surfaces with a roller retainer for preventing the axial movement of the rollers.
Claim 27
Dependent Claim
47 words
A portable artificial pancreas as defined in claim 24 wherein the roller holder is in the form of a short solid cylinder, and the tube guide groove is annular and is formed in the outer peripheral side surface of the roller holder over the entire circumference thereof.
Claim 28
Dependent Claim
20 words
A portable artificial pancreas as defined in claim 25 wherein the tube guide groove is substantially semicircular in cross section.
Claim 29
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 25 wherein the roller retainer is in the form of a disk concentric with the roller holder.
Claim 30
Dependent Claim
25 words
A portable artificial pancreas as defined in claim 23 wherein the roller holder is made of polytetrafluoroethylene, and the rollers are made of stainless steel.
Claim 31
Dependent Claim
122 words
A portable artificial pancreas as defined in claim 15 wherein the single assembly including the arithmetic control unit is provided for a plurality of sets of assemblies including the blood sugar detecting unit and assemblies including the injection unit, and the blood sugar detecting units each have a timer for determining transmitting time and repeatedly transmits an output signal to the control unit in a predetermined order, the control unit comprising a timer for emitting a standard signal corresponding to the transmitting time of each blood sugar detecting unit, a circuit for measuring the time lag between every signal received from each detecting unit and the corresponding standard signal and an alarm for giving warning when the lag exceeds a predetermined value.
References Cited (Backward Citations)
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