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EP0098431A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Pharmaceutical composition comprising immune globulin and fibronectin

Assignee: Bayer Corp
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Filing: 1983-06-18
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Granted: —
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Expires: 2003-06-18
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Abstract

Abstract There is disclosed a pharmaceutical composition for therapeutic use comprising an immune globulin and fibronectin in amounts sufficient to produce an opsonic activity in the composition that is greater than the additive opsonic activity of the individual agents or in amounts sufficient to produce a phagocytosis of infectious agents greater than the additive effect from fibronectin and immune globulin alone.

Inventors

  • 👤 John L. Lundblad
  • 👤 Miriam D. Budinger
  • 👤 Richard S. Schwartz

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-08 02:13
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/395; A61K39/40; A61P; A61P37/00; A61P37/02; A61P37/04

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 25 words
A pharmaceutical composition comprising purified immune globulin and fibronectin which contains 0.01 - 1000 parts of immune globulin per part of fibronectin, weight to weight.
Claim 2
Dependent Claim 25 words
A pharmaceutical composition comprising purified immune globulin and fibronectin which contains 0.01 - 1000 parts of immune globulin per part of fibronectin, weight to weight.
Claim 3
Dependent Claim 14 words
A composition according to claim 1,characterized in that it is a sterile aqueous solution.
Claim 4
Dependent Claim 25 words
A composition according to claim 1 or 2, characterized in that the concentration of immune globulin and fibronectin is 1 - 30 %,weight to volume.
Claim 5
Dependent Claim 33 words
A composition according to claim 3, characterized in that the immune globulin is intravenous immune globulin and the concentration of the immune globulin and fibronectin is 5 - 15 %, weight to volume.
Claim 6
Dependent Claim 33 words
A composition according to claim 3, characterized in that the immune globulin is intramuscular immune globulin and the concentration of the immune globulin and fibronectin is 10 - 20 %, weight to volume.
Claim 7
Dependent Claim 34 words
A composition according to any of claims 1 to 5, characterized in that it contains 0.1 - 500 parts, preferably 1 - 100 parts, of immune globulin per part of fibronectin, weight to weight.
Claim 8
Dependent Claim 20 words
A composition according to any of claims 1 to 6, characterized in that the immune globulin is immune serum globulin.
Claim 9
Dependent Claim 18 words
A composition according to claim 7, characterized in that the immune serum globulin is suitable for intravenous administration.
Claim 10
Dependent Claim 32 words
A pharmaceutical composition according to any of claims 1 to 8 which is suitable for intravenous administration for treatment of impaired reticuloendothelial system function and reduced ability for opsonization of infectious agents.
Claim 11
Dependent Claim 30 words
A composition according to any of claims 1 to 9, characterized in that it further includes a carbohydrate, the amount of carbohydrate preferably being 1 - 20 % by weight..

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