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EP0096982A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Manufacture of highlighted intagliated articles

Assignee: Syngenta Ltd
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Filing: 1983-05-23
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Granted: —
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Expires: 2003-05-23
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Abstract

Abstract Process for manufacturing coloured solid articles, e.g. pharmaceutical tablets, bearing at least one highlighted intagliation, which comprises (1) either (A) applying to said articles a film coating suspension comprising at least one defined optically anisotropic substance and at least one film coating agent, or (B) applying to said articles a suspension comprising at least one defined optically anisotropic substance but no film coating agent, and then (2) spraying the resulting articles with a solvent, and in which both of the steps (1) and (2) are carried out in a conventional film coating apparatus.

Inventors

  • 👤 Brian Leight Corfield
  • 👤 Raymond Charles Rowe

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-07 15:50
CPC Classifications
B; B05; B05D; B05D5/00; B05D5/06; A; A23; A23G; A23G3/00; A23G3/02; A23G3/28; A23G3/34; A23G3/50; A23G3/54; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/28; B05D2258/00

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 192 words
A process for the manufacture of coloured solid articles bearing at least one highlighted intagliation, which comprises: (1) either (A) applying to coloured intagliated articles, which themselves may be uncoated or film coated, a film coating suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00 and at least one film coating agent, the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; or (B) applying to coloured intagliated articles, which themselves may be uncoated or film coated, a suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00, but no film coating agent, and the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; and characterised in that: (2) the resulting coloured solid articles bearing at least one highlighted intagliation are sprayed with a solvent in a conventional film coating apparatus in such a way that a rubbing action takes place between the said articles.
Claim 2
Dependent Claim 192 words
A process for the manufacture of coloured solid articles bearing at least one highlighted intagliation, which comprises: (1) either (A) applying to coloured intagliated articles, which themselves may be uncoated or film coated, a film coating suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00 and at least one film coating agent, the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; or (B) applying to coloured intagliated articles, which themselves may be uncoated or film coated, a suspension comprising at least one optically anisotropic substance having a minimum refractive index not greater than 2.00, but no film coating agent, and the application being carried out in a conventional film coating apparatus in such a way that a rubbing action takes place between the articles being coated; and characterised in that: (2) the resulting coloured solid articles bearing at least one highlighted intagliation are sprayed with a solvent in a conventional film coating apparatus in such a way that a rubbing action takes place between the said articles.
Claim 3
Dependent Claim 36 words
A process as claimed in claim 1 in which the coloured intagliated article is a pharmaceutical or veterinary unit dosage form or a piece of sugar confectionery having approximately the same dimensions as a pharmaceutical tablet.
Claim 4
Dependent Claim 22 words
A process as claimed in claim 2 in which the pharmaceutical or veterinary unit dosage form is a pharmaceutical or veterinary tablet.
Claim 5
Dependent Claim 92 words
A process as claimed in claim 1 in which the said coloured solid articles bearing at least one highlighted intagliation either have no film coating agent on their outer surface or they have a relatively water-soluble film coating agent on their outer surface, and in which the said solvent used in step (2) is (a) water, (b) a mixture of water and a (1-4C)alkanol, (c) a mixture of a polyhalogenated (1-4C)alkane and a (1-4C)alkanol, or (d) a mixture of solvent (c) and a dialkyl ketone of not more than 6 carbon atoms.
Claim 6
Dependent Claim 17 words
A process as claimed in claim 4 in which the said solvent contains at least one humectant.
Claim 7
Dependent Claim 22 words
A process as claimed in claim 5 in which the humectant is glycerol, propylene glycol, or a low molecular weight polyethylene glycol.
Claim 8
Dependent Claim 13 words
A process as claimed in claim 4 in which the solvent is water.
Claim 9
Dependent Claim 75 words
A process as claimed in claim 1 in which the said coloured solid articles bearing at least one highlighted intagliation have a relatively water-insoluble film coating agent on their outer surface, and in which the said solvent used in step (2) is (e) a polyhalogenated (1-4C)alkane, (f) a dialkyl ketone of not more than 6 carbon atoms, (g) a mixture of solvents (e) and (f), or (h) a mixture of solvent (g) and a (1-4C)alkanol.
Claim 10
Dependent Claim 28 words
A process as claimed in claim 8 in which the said solvent contains at least one plasticiser which is suitable for the said relatively water-insoluble film coating agent.
Claim 11
Dependent Claim 27 words
A process as claimed in claim 9 in which the plasticiser is a di-(1-4C)alkyl phthalate, an ester of glycerol with an alkanoic acid, or a vegetable oil.
Claim 12
Dependent Claim 19 words
A coloured solid article bearing at least one highlighted intagliation, whenever manufactured by a process claimed in claim 1.

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